van Kuilenburg AB - Search Results

1

Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure.

van Kuilenburg AB, Dobritzsch D, Meinsma R, Haasjes J, Waterham HR, Nowaczyk MJ, Maropoulos GD, Hein G, Kalhoff H, Kirk JM, Baaske H, Aukett A, Duley JA, Ward KP, Lindqvist Y, van Gennip AH. van Kuilenburg AB, et al. Among authors: van gennip ah. Biochem J. 2002 May 15;364(Pt 1):157-63. doi: 10.1042/bj3640157. Biochem J. 2002. PMID: 11988088 Free PMC article.

2

Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-beta-D-arabinofuranosyl cytosine in a human T-lymphoblastic cell line.

Verschuur AC, Van Gennip AH, Leen R, Voûte PA, Brinkman J, Van Kuilenburg AB. Verschuur AC, et al. Among authors: van gennip ah, van kuilenburg ab. Int J Cancer. 2002 Apr 1;98(4):616-23. doi: 10.1002/ijc.10211. Int J Cancer. 2002. PMID: 11920624

3

Reduced 5-FU clearance in a patient with low DPD activity due to heterozygosity for a mutant allele of the DPYD gene.

Maring JG, van Kuilenburg AB, Haasjes J, Piersma H, Groen HJ, Uges DR, Van Gennip AH, De Vries EG. Maring JG, et al. Among authors: van gennip ah, van kuilenburg ab. Br J Cancer. 2002 Apr 8;86(7):1028-33. doi: 10.1038/sj.bjc.6600208. Br J Cancer. 2002. PMID: 11953843 Free PMC article.

4

Increased risk of grade IV neutropenia after administration of 5-fluorouracil due to a dihydropyrimidine dehydrogenase deficiency: high prevalence of the IVS14+1g>a mutation.

Van Kuilenburg AB, Meinsma R, Zoetekouw L, Van Gennip AH. Van Kuilenburg AB, et al. Among authors: van gennip ah. Int J Cancer. 2002 Sep 20;101(3):253-8. doi: 10.1002/ijc.10599. Int J Cancer. 2002. PMID: 12209976

5

Retinoic acid reduces the cytotoxicity of cyclopentenyl cytosine in neuroblastoma cells.

Bierau J, van Gennip AH, Leen R, Caron HN, van Kuilenburg AB. Bierau J, et al. Among authors: van gennip ah, van kuilenburg ab. FEBS Lett. 2002 Sep 11;527(1-3):229-33. doi: 10.1016/s0014-5793(02)03234-9. FEBS Lett. 2002. PMID: 12220665 Free article.

6

High prevalence of the IVS14 + 1G>A mutation in the dihydropyrimidine dehydrogenase gene of patients with severe 5-fluorouracil-associated toxicity.

Van Kuilenburg AB, Meinsma R, Zoetekouw L, Van Gennip AH. Van Kuilenburg AB, et al. Among authors: van gennip ah. Pharmacogenetics. 2002 Oct;12(7):555-8. doi: 10.1097/00008571-200210000-00007. Pharmacogenetics. 2002. PMID: 12360106

7

Histone deacetylases (HDACs): characterization of the classical HDAC family.

de Ruijter AJ, van Gennip AH, Caron HN, Kemp S, van Kuilenburg AB. de Ruijter AJ, et al. Among authors: van gennip ah, van kuilenburg ab. Biochem J. 2003 Mar 15;370(Pt 3):737-49. doi: 10.1042/BJ20021321. Biochem J. 2003. PMID: 12429021 Free PMC article. Review.

8

Cyclopentenyl cytosine primes SK-N-BE(2)c neuroblastoma cells for cytarabine toxicity.

Bierau J, Van Gennip AH, Leen R, Helleman J, Caron HN, Van Kuilenburg AB. Bierau J, et al. Among authors: van gennip ah, van kuilenburg ab. Int J Cancer. 2003 Jan 20;103(3):387-92. doi: 10.1002/ijc.10858. Int J Cancer. 2003. PMID: 12471622

9

Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency.

van Kuilenburg AB, De Abreu RA, van Gennip AH. van Kuilenburg AB, et al. Among authors: van gennip ah. Ann Clin Biochem. 2003 Jan;40(Pt 1):41-5. doi: 10.1258/000456303321016150. Ann Clin Biochem. 2003. PMID: 12542909 Review.

10

Combination therapy in childhood leukaemia: in vitro studies of thiopurines and inhibitors of purine metabolism on apoptosis.

De Abreu RA, Trueworthy RC, van Kuilenburg AB, Vogels-Mentink TM, Lambooy LH, van Gennip AH. De Abreu RA, et al. Among authors: van gennip ah, van kuilenburg ab. Ann Clin Biochem. 2003 Jan;40(Pt 1):70-4. doi: 10.1258/000456303321016196. Ann Clin Biochem. 2003. PMID: 12542913

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