Allen MJ - Search Results

1

Identification of potent and selective oxytocin antagonists. Part 2: further investigation of benzofuran derivatives.

Wyatt PG, Allen MJ, Chilcott J, Gardner CJ, Livermore DG, Mordaunt JE, Nerozzi F, Patel M, Perren MJ, Weingarten GG, Shabbir S, Woollard PM, Zhou P. Wyatt PG, et al. Among authors: allen mj. Bioorg Med Chem Lett. 2002 May 20;12(10):1405-11. doi: 10.1016/s0960-894x(02)00160-9. Bioorg Med Chem Lett. 2002. PMID: 11992787

2

Identification of potent and selective oxytocin antagonists. Part 1: indole and benzofuran derivatives.

Wyatt PG, Allen MJ, Chilcott J, Foster A, Livermore DG, Mordaunt JE, Scicinski J, Woollard PM. Wyatt PG, et al. Among authors: allen mj. Bioorg Med Chem Lett. 2002 May 20;12(10):1399-404. doi: 10.1016/s0960-894x(02)00159-2. Bioorg Med Chem Lett. 2002. PMID: 11992786

3

2,5-Diketopiperazines as potent and selective oxytocin antagonists 1: Identification, stereochemistry and initial SAR.

Wyatt PG, Allen MJ, Borthwick AD, Davies DE, Exall AM, Hatley RJ, Irving WR, Livermore DG, Miller ND, Nerozzi F, Sollis SL, Szardenings AK. Wyatt PG, et al. Among authors: allen mj. Bioorg Med Chem Lett. 2005 May 16;15(10):2579-82. doi: 10.1016/j.bmcl.2005.03.045. Bioorg Med Chem Lett. 2005. PMID: 15863320

4

2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 2. Synthesis, chirality, and pharmacokinetics.

Borthwick AD, Davies DE, Exall AM, Livermore DG, Sollis SL, Nerozzi F, Allen MJ, Perren M, Shabbir SS, Woollard PM, Wyatt PG. Borthwick AD, et al. Among authors: allen mj. J Med Chem. 2005 Nov 3;48(22):6956-69. doi: 10.1021/jm050557v. J Med Chem. 2005. PMID: 16250654

5

2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists. 3. Synthesis, pharmacokinetics, and in vivo potency.

Borthwick AD, Davies DE, Exall AM, Hatley RJ, Hughes JA, Irving WR, Livermore DG, Sollis SL, Nerozzi F, Valko KL, Allen MJ, Perren M, Shabbir SS, Woollard PM, Price MA. Borthwick AD, et al. Among authors: allen mj. J Med Chem. 2006 Jul 13;49(14):4159-70. doi: 10.1021/jm060073e. J Med Chem. 2006. PMID: 16821776

6

The discovery of GSK221149A: a potent and selective oxytocin antagonist.

Liddle J, Allen MJ, Borthwick AD, Brooks DP, Davies DE, Edwards RM, Exall AM, Hamlett C, Irving WR, Mason AM, McCafferty GP, Nerozzi F, Peace S, Philp J, Pollard D, Pullen MA, Shabbir SS, Sollis SL, Westfall TD, Woollard PM, Wu C, Hickey DM. Liddle J, et al. Among authors: allen mj. Bioorg Med Chem Lett. 2008 Jan 1;18(1):90-4. doi: 10.1016/j.bmcl.2007.11.008. Epub 2007 Nov 6. Bioorg Med Chem Lett. 2008. PMID: 18032036

7

Pyridyl-2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency.

Borthwick AD, Liddle J, Davies DE, Exall AM, Hamlett C, Hickey DM, Mason AM, Smith IE, Nerozzi F, Peace S, Pollard D, Sollis SL, Allen MJ, Woollard PM, Pullen MA, Westfall TD, Stanislaus DJ. Borthwick AD, et al. Among authors: allen mj. J Med Chem. 2012 Jan 26;55(2):783-96. doi: 10.1021/jm201287w. Epub 2012 Jan 12. J Med Chem. 2012. PMID: 22239250

8

Structure-activity relationship investigations of a potent and selective benzodiazepine oxytocin antagonist.

Wyatt PG, Allen MJ, Chilcott J, Hickin G, Miller ND, Woollard PM. Wyatt PG, et al. Among authors: allen mj. Bioorg Med Chem Lett. 2001 May 21;11(10):1301-5. doi: 10.1016/s0960-894x(01)00202-5. Bioorg Med Chem Lett. 2001. PMID: 11392542

9

Oxytocin antagonists as potential therapeutic agents for the treatment of preterm labour.

Allen MJ, Livermore DG, Mordaunt JE. Allen MJ, et al. Prog Med Chem. 2006;44:331-73. doi: 10.1016/S0079-6468(05)44407-0. Prog Med Chem. 2006. PMID: 16697900 Review. No abstract available.

10

Use of a novel and highly selective oxytocin receptor antagonist to characterize uterine contractions in the rat.

McCafferty GP, Pullen MA, Wu C, Edwards RM, Allen MJ, Woollard PM, Borthwick AD, Liddle J, Hickey DM, Brooks DP, Westfall TD. McCafferty GP, et al. Among authors: allen mj. Am J Physiol Regul Integr Comp Physiol. 2007 Jul;293(1):R299-305. doi: 10.1152/ajpregu.00057.2007. Epub 2007 Mar 29. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17395790 Free article.

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