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A phase I trial of the dual farnesyltransferase and geranylgeranyltransferase inhibitor L-778,123 and radiotherapy for locally advanced pancreatic cancer.
Martin NE, Brunner TB, Kiel KD, DeLaney TF, Regine WF, Mohiuddin M, Rosato EF, Haller DG, Stevenson JP, Smith D, Pramanik B, Tepper J, Tanaka WK, Morrison B, Deutsch P, Gupta AK, Muschel RJ, McKenna WG, Bernhard EJ, Hahn SM. Martin NE, et al. Among authors: deutsch p. Clin Cancer Res. 2004 Aug 15;10(16):5447-54. doi: 10.1158/1078-0432.CCR-04-0248. Clin Cancer Res. 2004. PMID: 15328183 Clinical Trial.
Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.
Lobell RB, Liu D, Buser CA, Davide JP, DePuy E, Hamilton K, Koblan KS, Lee Y, Mosser S, Motzel SL, Abbruzzese JL, Fuchs CS, Rowinsky EK, Rubin EH, Sharma S, Deutsch PJ, Mazina KE, Morrison BW, Wildonger L, Yao SL, Kohl NE. Lobell RB, et al. Among authors: deutsch pj. Mol Cancer Ther. 2002 Jul;1(9):747-58. Mol Cancer Ther. 2002. PMID: 12479371
Characterization of a novel prostate-specific antigen-activated peptide-doxorubicin conjugate in patients with prostate cancer.
DiPaola RS, Rinehart J, Nemunaitis J, Ebbinghaus S, Rubin E, Capanna T, Ciardella M, Doyle-Lindrud S, Goodwin S, Fontaine M, Adams N, Williams A, Schwartz M, Winchell G, Wickersham K, Deutsch P, Yao SL. DiPaola RS, et al. Among authors: deutsch p. J Clin Oncol. 2002 Apr 1;20(7):1874-9. doi: 10.1200/JCO.2002.07.001. J Clin Oncol. 2002. PMID: 11919247 Clinical Trial.
The effect of MK-0524, a prostaglandin D(2) receptor antagonist, on prostaglandin D (2)-induced nasal airway obstruction in healthy volunteers.
Van Hecken A, Depré M, De Lepeleire I, Thach C, Oeyen M, Van Effen J, Laethem T, Mazina K, Crumley T, Wenning L, Gottesdiener KM, Deutsch P, Clement P, Lai E, de Hoon JN. Van Hecken A, et al. Among authors: deutsch p. Eur J Clin Pharmacol. 2007 Feb;63(2):135-41. doi: 10.1007/s00228-006-0211-2. Epub 2007 Jan 3. Eur J Clin Pharmacol. 2007. PMID: 17200838 Clinical Trial.
113 results