Kerwin SM - Search Results

1

Investigation of quadruplex oligonucleotide-drug interactions by electrospray ionization mass spectrometry.

David WM, Brodbelt J, Kerwin SM, Thomas PW. David WM, et al. Among authors: kerwin sm. Anal Chem. 2002 May 1;74(9):2029-33. doi: 10.1021/ac011283w. Anal Chem. 2002. PMID: 12033303

2

Self-assembly of a quinobenzoxazine-Mg2+ complex on DNA: a new paradigm for the structure of a drug-DNA complex and implications for the structure of the quinolone bacterial gyrase-DNA complex.

Fan JY, Sun D, Yu H, Kerwin SM, Hurley LH. Fan JY, et al. Among authors: kerwin sm. J Med Chem. 1995 Feb 3;38(3):408-24. doi: 10.1021/jm00003a003. J Med Chem. 1995. PMID: 7853333

3

NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.

Fedoroff OY, Salazar M, Han H, Chemeris VV, Kerwin SM, Hurley LH. Fedoroff OY, et al. Among authors: kerwin sm. Biochemistry. 1998 Sep 8;37(36):12367-74. doi: 10.1021/bi981330n. Biochemistry. 1998. PMID: 9730808

4

G-Quadruplex DNA as a target for drug design.

Kerwin SM. Kerwin SM. Curr Pharm Des. 2000 Mar;6(4):441-78. doi: 10.2174/1381612003400849. Curr Pharm Des. 2000. PMID: 10788591 Review.

5

Synthesis of a heterocyclic aza-enediyne and its DNA-cleavage properties.

David WM, Kumar D, Kerwin SM. David WM, et al. Among authors: kerwin sm. Bioorg Med Chem Lett. 2000 Nov 20;10(22):2509-12. doi: 10.1016/s0960-894x(00)00516-3. Bioorg Med Chem Lett. 2000. PMID: 11086717

6

G-quadruplex DNA binding by a series of carbocyanine dyes.

Kerwin SM, Sun D, Kern JT, Rangan A, Thomas PW. Kerwin SM, et al. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2411-4. doi: 10.1016/s0960-894x(01)00490-5. Bioorg Med Chem Lett. 2001. PMID: 11549435

7

N-propargyl-2-alkynylbenzothiazolium aza-enediynes: role of the 2-alkynylbenzothiazolium functionality in DNA cleavage.

Kumar D, David WM, Kerwin SM. Kumar D, et al. Among authors: kerwin sm. Bioorg Med Chem Lett. 2001 Nov 19;11(22):2971-4. doi: 10.1016/s0960-894x(01)00606-0. Bioorg Med Chem Lett. 2001. PMID: 11677138

8

Evaluation of complexation of metal-mediated DNA-binding drugs to oligonucleotides via electrospray ionization mass spectrometry.

Reyzer ML, Brodbelt JS, Kerwin SM, Kumar D. Reyzer ML, et al. Among authors: kerwin sm. Nucleic Acids Res. 2001 Nov 1;29(21):E103-3. doi: 10.1093/nar/29.21.e103. Nucleic Acids Res. 2001. PMID: 11691940 Free PMC article.

9

Perylene diimide G-quadruplex DNA binding selectivity is mediated by ligand aggregation.

Kerwin SM, Chen G, Kern JT, Thomas PW. Kerwin SM, et al. Bioorg Med Chem Lett. 2002 Feb 11;12(3):447-50. doi: 10.1016/s0960-894x(01)00775-2. Bioorg Med Chem Lett. 2002. PMID: 11814817

10

DNA modification by 4-aza-3-ene-1,6-diynes: DNA cleavage, pH-dependent cytosine-specific interactions, and cancer cell cytotoxicity.

Tuntiwechapikul W, David WM, Kumar D, Salazar M, Kerwin SM. Tuntiwechapikul W, et al. Among authors: kerwin sm. Biochemistry. 2002 Apr 23;41(16):5283-90. doi: 10.1021/bi025535e. Biochemistry. 2002. PMID: 11955078

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