Konrad M - Search Results

1

Structural characterization of the closed conformation of mouse guanylate kinase.

Sekulic N, Shuvalova L, Spangenberg O, Konrad M, Lavie A. Sekulic N, et al. Among authors: konrad m. J Biol Chem. 2002 Aug 16;277(33):30236-43. doi: 10.1074/jbc.M204668200. Epub 2002 May 29. J Biol Chem. 2002. PMID: 12036965 Free article.

2

Structural basis for nucleotide-dependent regulation of membrane-associated guanylate kinase-like domains.

Li Y, Spangenberg O, Paarmann I, Konrad M, Lavie A. Li Y, et al. Among authors: konrad m. J Biol Chem. 2002 Feb 8;277(6):4159-65. doi: 10.1074/jbc.M110792200. Epub 2001 Nov 29. J Biol Chem. 2002. PMID: 11729206 Free article.

3

Formation of complexes between Ca2+.calmodulin and the synapse-associated protein SAP97 requires the SH3 domain-guanylate kinase domain-connecting HOOK region.

Paarmann I, Spangenberg O, Lavie A, Konrad M. Paarmann I, et al. Among authors: konrad m. J Biol Chem. 2002 Oct 25;277(43):40832-8. doi: 10.1074/jbc.M205618200. Epub 2002 Aug 19. J Biol Chem. 2002. PMID: 12189141 Free article.

4

Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase.

Lavie A, Konrad M. Lavie A, et al. Among authors: konrad m. Mini Rev Med Chem. 2004 May;4(4):351-9. doi: 10.2174/1389557043403981. Mini Rev Med Chem. 2004. PMID: 15134538 Review.

5

Substrate-induced conformational changes in human UMP/CMP kinase.

Segura-Peña D, Sekulic N, Ort S, Konrad M, Lavie A. Segura-Peña D, et al. Among authors: konrad m. J Biol Chem. 2004 Aug 6;279(32):33882-9. doi: 10.1074/jbc.M401989200. Epub 2004 May 26. J Biol Chem. 2004. PMID: 15163660 Free article.

6

Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine.

Malito E, Sekulic N, Too WC, Konrad M, Lavie A. Malito E, et al. Among authors: konrad m. J Mol Biol. 2006 Nov 24;364(2):136-51. doi: 10.1016/j.jmb.2006.08.084. Epub 2006 Sep 3. J Mol Biol. 2006. PMID: 17007874 Free PMC article.

7

Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation.

Sekulic N, Konrad M, Lavie A. Sekulic N, et al. Among authors: konrad m. J Biol Chem. 2007 Jul 27;282(30):22112-21. doi: 10.1074/jbc.M701713200. Epub 2007 May 31. J Biol Chem. 2007. PMID: 17540769 Free article.

8

The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): implications for the development of dCK-activated acyclic guanine analogues.

Hazra S, Konrad M, Lavie A. Hazra S, et al. Among authors: konrad m. J Med Chem. 2010 Aug 12;53(15):5792-800. doi: 10.1021/jm1005379. J Med Chem. 2010. PMID: 20684612 Free PMC article.

9

Modifying human thymidylate kinase to potentiate azidothymidine activation.

Brundiers R, Lavie A, Veit T, Reinstein J, Schlichting I, Ostermann N, Goody RS, Konrad M. Brundiers R, et al. Among authors: konrad m. J Biol Chem. 1999 Dec 10;274(50):35289-92. doi: 10.1074/jbc.274.50.35289. J Biol Chem. 1999. PMID: 10585390 Free article.

10

Binding of nucleotides to guanylate kinase, p21(ras), and nucleoside-diphosphate kinase studied by nano-electrospray mass spectrometry.

Prinz H, Lavie A, Scheidig AJ, Spangenberg O, Konrad M. Prinz H, et al. Among authors: konrad m. J Biol Chem. 1999 Dec 10;274(50):35337-42. doi: 10.1074/jbc.274.50.35337. J Biol Chem. 1999. PMID: 10585400 Free article.

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