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Nuclear receptor Nurr1 is expressed in and is associated with human restenosis and inhibits vascular lesion formation in mice involving inhibition of smooth muscle cell proliferation and inflammation.
Bonta PI, Pols TW, van Tiel CM, Vos M, Arkenbout EK, Rohlena J, Koch KT, de Maat MP, Tanck MW, de Winter RJ, Pannekoek H, Biessen EA, Bot I, de Vries CJ. Bonta PI, et al. Among authors: pannekoek h. Circulation. 2010 May 11;121(18):2023-32. doi: 10.1161/CIRCULATIONAHA.109.885673. Epub 2010 Apr 26. Circulation. 2010. PMID: 20421523
Activin A induces a non-fibrotic phenotype in smooth muscle cells in contrast to TGF-β.
Groenendijk BC, Benus GF, Klous A, Pacheco YM, Volger OL, Fledderus JO, Ferreira V, Engelse MA, Pannekoek H, ten Dijke P, Horrevoets AJ, de Vries CJ. Groenendijk BC, et al. Among authors: pannekoek h. Exp Cell Res. 2011 Jan 15;317(2):131-42. doi: 10.1016/j.yexcr.2010.10.007. Epub 2010 Oct 15. Exp Cell Res. 2011. PMID: 20955695
147 results