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1,078 results

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Page 1
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities.
Cappelli A, Anzini M, Vomero S, Mennuni L, Makovec F, Doucet E, Hamon M, Menziani MC, De Benedetti PG, Giorgi G, Ghelardini C, Collina S. Cappelli A, et al. Among authors: hamon m. Bioorg Med Chem. 2002 Mar;10(3):779-801. doi: 10.1016/s0968-0896(01)00332-7. Bioorg Med Chem. 2002. PMID: 11814868
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.
Cappelli A, Anzini M, Vomero S, Canullo L, Mennuni L, Makovec F, Doucet E, Hamon M, Menziani MC, De Benedetti PG, Bruni G, Romeo MR, Giorgi G, Donati A. Cappelli A, et al. Among authors: hamon m. J Med Chem. 1999 May 6;42(9):1556-75. doi: 10.1021/jm981112s. J Med Chem. 1999. PMID: 10229626
Novel, potent, and selective quinoxaline-based 5-HT(3) receptor ligands. 1. Further structure-activity relationships and pharmacological characterization.
Butini S, Budriesi R, Hamon M, Morelli E, Gemma S, Brindisi M, Borrelli G, Novellino E, Fiorini I, Ioan P, Chiarini A, Cagnotto A, Mennini T, Fracasso C, Caccia S, Campiani G. Butini S, et al. Among authors: hamon m. J Med Chem. 2009 Nov 12;52(21):6946-50. doi: 10.1021/jm901126m. J Med Chem. 2009. PMID: 19831400
Pyrroloquinoxaline derivatives as high-affinity and selective 5-HT(3) receptor agonists: synthesis, further structure-activity relationships, and biological studies.
Campiani G, Morelli E, Gemma S, Nacci V, Butini S, Hamon M, Novellino E, Greco G, Cagnotto A, Goegan M, Cervo L, Dalla Valle F, Fracasso C, Caccia S, Mennini T. Campiani G, et al. Among authors: hamon m. J Med Chem. 1999 Oct 21;42(21):4362-79. doi: 10.1021/jm990151g. J Med Chem. 1999. PMID: 10543880
Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.
Morelli E, Gemma S, Budriesi R, Campiani G, Novellino E, Fattorusso C, Catalanotti B, Coccone SS, Ros S, Borrelli G, Persico M, Fiorini I, Nacci V, Ioan P, Chiarini A, Hamon M, Cagnotto A, Mennini T, Fracasso C, Colovic M, Caccia S, Butini S. Morelli E, et al. Among authors: hamon m. J Med Chem. 2009 Jun 11;52(11):3548-62. doi: 10.1021/jm900018b. J Med Chem. 2009. PMID: 19425598
Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines.
Prunier H, Rault S, Lancelot JC, Robba M, Renard P, Delagrange P, Pfeiffer B, Caignard DH, Misslin R, Guardiola-Lemaitre B, Hamon M. Prunier H, et al. Among authors: hamon m. J Med Chem. 1997 Jun 6;40(12):1808-19. doi: 10.1021/jm960501o. J Med Chem. 1997. PMID: 9191957
1,078 results