Uren RT - Search Results

1

SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, Alexander WS. Krebs DL, et al. Among authors: uren rt. Mol Cell Biol. 2002 Jul;22(13):4567-78. doi: 10.1128/MCB.22.13.4567-4578.2002. Mol Cell Biol. 2002. PMID: 12052866 Free PMC article.

2

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.

Greenhalgh CJ, Metcalf D, Thaus AL, Corbin JE, Uren R, Morgan PO, Fabri LJ, Zhang JG, Martin HM, Willson TA, Billestrup N, Nicola NA, Baca M, Alexander WS, Hilton DJ. Greenhalgh CJ, et al. J Biol Chem. 2002 Oct 25;277(43):40181-4. doi: 10.1074/jbc.C200450200. Epub 2002 Sep 2. J Biol Chem. 2002. PMID: 12208853 Free article.

3

A novel role of suppressor of cytokine signaling-2 in the regulation of TrkA neurotrophin receptor biology.

Uren RT, Turbić A, Wong AW, Klein R, Murray SS, Turnley AM. Uren RT, et al. J Neurochem. 2014 May;129(4):614-27. doi: 10.1111/jnc.12671. Epub 2014 Mar 4. J Neurochem. 2014. PMID: 24484474 Free article.

4

Probing BAK and BAX Activation and Pore Assembly with Cytochrome c Release, Limited Proteolysis, and Oxidant-Induced Linkage.

Iyer S, Uren RT, Kluck RM. Iyer S, et al. Among authors: uren rt. Methods Mol Biol. 2019;1877:201-216. doi: 10.1007/978-1-4939-8861-7_14. Methods Mol Biol. 2019. PMID: 30536008

5

A lipid signature of BAK-driven apoptotic pore formation.

Uren RT, Ritchie ME, Wong AW, Ludeman JP, Uno E, Narayana VK, De Souza DP, Sviridov D, Kluck RM. Uren RT, et al. bioRxiv [Preprint]. 2024 Nov 13:2024.10.16.618570. doi: 10.1101/2024.10.16.618570. bioRxiv. 2024. PMID: 39463966 Free PMC article. Preprint.

6

Mitochondrial release of pro-apoptotic proteins: electrostatic interactions can hold cytochrome c but not Smac/DIABLO to mitochondrial membranes.

Uren RT, Dewson G, Bonzon C, Lithgow T, Newmeyer DD, Kluck RM. Uren RT, et al. J Biol Chem. 2005 Jan 21;280(3):2266-74. doi: 10.1074/jbc.M411106200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15537572 Free article.

7

Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.

Uren RT, Dewson G, Chen L, Coyne SC, Huang DC, Adams JM, Kluck RM. Uren RT, et al. J Cell Biol. 2007 Apr 23;177(2):277-87. doi: 10.1083/jcb.200606065. J Cell Biol. 2007. PMID: 17452531 Free PMC article.

8

Bak core and latch domains separate during activation, and freed core domains form symmetric homodimers.

Brouwer JM, Westphal D, Dewson G, Robin AY, Uren RT, Bartolo R, Thompson GV, Colman PM, Kluck RM, Czabotar PE. Brouwer JM, et al. Among authors: uren rt. Mol Cell. 2014 Sep 18;55(6):938-946. doi: 10.1016/j.molcel.2014.07.016. Epub 2014 Aug 28. Mol Cell. 2014. PMID: 25175025 Free article.

9

Regulation of neurotrophin receptor (Trk) signaling: suppressor of cytokine signaling 2 (SOCS2) is a new player.

Uren RT, Turnley AM. Uren RT, et al. Front Mol Neurosci. 2014 May 14;7:39. doi: 10.3389/fnmol.2014.00039. eCollection 2014. Front Mol Neurosci. 2014. PMID: 24860421 Free PMC article. Review.

10

The BCL-2 family member BID plays a role during embryonic development in addition to its BH3-only protein function by acting in parallel to BAX, BAK and BOK.

Ke FS, Holloway S, Uren RT, Wong AW, Little MH, Kluck RM, Voss AK, Strasser A. Ke FS, et al. Among authors: uren rt. EMBO J. 2022 Aug 1;41(15):e110300. doi: 10.15252/embj.2021110300. Epub 2022 Jun 27. EMBO J. 2022. PMID: 35758142 Free PMC article.

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