Cloning and expression of a single-chain catalytic antibody that acts as a glutathione peroxidase mimic with high catalytic efficiency.
Ren X, Gao S, You D, Huang H, Liu Z, Mu Y, Liu J, Zhang Y, Yan G, Luo G, Yang T, Shen J.
Ren X, et al. Among authors: liu z, liu j.
Biochem J. 2001 Oct 15;359(Pt 2):369-74. doi: 10.1042/0264-6021:3590369.
Biochem J. 2001.
PMID: 11583583
Free PMC article.
In previous papers we have developed a new strategy for generating abzymes: the monoclonal antibody with a substrate-binding site is first prepared, then a catalytic group is incorporated into the monoclonal antibody's binding site by using chemical mutation [Luo, Zhu, Ding, Gao, …
In previous papers we have developed a new strategy for generating abzymes: the monoclonal antibody with a substrate-binding site is first p …