Lai VC - Search Results

1

Mutations in NS5B polymerase of hepatitis C virus: impacts on in vitro enzymatic activity and viral RNA replication in the subgenomic replicon cell culture.

Cheney IW, Naim S, Lai VC, Dempsey S, Bellows D, Walker MP, Shim JH, Horscroft N, Hong Z, Zhong W. Cheney IW, et al. Among authors: lai vc. Virology. 2002 Jun 5;297(2):298-306. doi: 10.1006/viro.2002.1461. Virology. 2002. PMID: 12083828 Free article.

2

Canonical 3'-deoxyribonucleotides as a chain terminator for HCV NS5B RNA-dependent RNA polymerase.

Shim J, Larson G, Lai V, Naim S, Wu JZ. Shim J, et al. Antiviral Res. 2003 May;58(3):243-51. doi: 10.1016/s0166-3542(03)00007-x. Antiviral Res. 2003. PMID: 12767472

3

Comparative analysis of anti-hepatitis C virus activity and gene expression mediated by alpha, beta, and gamma interferons.

Cheney IW, Lai VC, Zhong W, Brodhag T, Dempsey S, Lim C, Hong Z, Lau JY, Tam RC. Cheney IW, et al. Among authors: lai vc. J Virol. 2002 Nov;76(21):11148-54. doi: 10.1128/jvi.76.21.11148-11154.2002. J Virol. 2002. PMID: 12368359 Free PMC article.

4

In vitro RNA replication directed by replicase complexes isolated from the subgenomic replicon cells of hepatitis C virus.

Lai VC, Dempsey S, Lau JY, Hong Z, Zhong W. Lai VC, et al. J Virol. 2003 Feb;77(3):2295-300. doi: 10.1128/jvi.77.3.2295-2300.2003. J Virol. 2003. PMID: 12525668 Free PMC article.

5

Establishment of a subgenomic replicon for bovine viral diarrhea virus in Huh-7 cells and modulation of interferon-regulated factor 3-mediated antiviral response.

Horscroft N, Bellows D, Ansari I, Lai VC, Dempsey S, Liang D, Donis R, Zhong W, Hong Z. Horscroft N, et al. Among authors: lai vc. J Virol. 2005 Mar;79(5):2788-96. doi: 10.1128/JVI.79.5.2788-2796.2005. J Virol. 2005. PMID: 15708997 Free PMC article.

6

Replicon cell culture system as a valuable tool in antiviral drug discovery against hepatitis C virus.

Horscroft N, Lai VC, Cheney W, Yao N, Wu JZ, Hong Z, Zhong W. Horscroft N, et al. Among authors: lai vc. Antivir Chem Chemother. 2005;16(1):1-12. doi: 10.1177/095632020501600101. Antivir Chem Chemother. 2005. PMID: 15739617 Free article. Review.

7

Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agents.

Varaprasad CV, Ramasamy KS, Girardet JL, Gunic E, Lai V, Zhong W, An H, Hong Z. Varaprasad CV, et al. Bioorg Chem. 2007 Feb;35(1):25-34. doi: 10.1016/j.bioorg.2006.07.003. Epub 2006 Sep 1. Bioorg Chem. 2007. PMID: 16945403

8

Synthesis of new 2'-beta-C-methyl related triciribine analogues as anti-HCV agents.

Smith KL, Lai VC, Prigaro BJ, Ding Y, Gunic E, Girardet JL, Zhong W, Hong Z, Lang S, An H. Smith KL, et al. Among authors: lai vc. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3517-20. doi: 10.1016/j.bmcl.2004.04.067. Bioorg Med Chem Lett. 2004. PMID: 15177464

9

Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase.

Ding Y, Girardet JL, Smith KL, Larson G, Prigaro B, Lai VC, Zhong W, Wu JZ. Ding Y, et al. Among authors: lai vc. Bioorg Med Chem Lett. 2005 Feb 1;15(3):675-8. doi: 10.1016/j.bmcl.2004.11.028. Bioorg Med Chem Lett. 2005. PMID: 15664835

10

Synthesis of 9-(2-beta-C-methyl-beta-d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication.

Ding Y, Girardet JL, Hong Z, Lai VC, An H, Koh YH, Shaw SZ, Zhong W. Ding Y, et al. Among authors: lai vc. Bioorg Med Chem Lett. 2005 Feb 1;15(3):709-13. doi: 10.1016/j.bmcl.2004.11.020. Bioorg Med Chem Lett. 2005. PMID: 15664842

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