Sessa WC - Search Results

1

Native low-density lipoprotein induces endothelial nitric oxide synthase dysfunction: role of heat shock protein 90 and caveolin-1.

Pritchard KA, Ackerman AW, Ou J, Curtis M, Smalley DM, Fontana JT, Stemerman MB, Sessa WC. Pritchard KA, et al. Among authors: sessa wc. Free Radic Biol Med. 2002 Jul 1;33(1):52-62. doi: 10.1016/s0891-5849(02)00851-1. Free Radic Biol Med. 2002. PMID: 12086682

2

Heat shock protein 90 and tyrosine kinase regulate eNOS NO* generation but not NO* bioactivity.

Ou J, Fontana JT, Ou Z, Jones DW, Ackerman AW, Oldham KT, Yu J, Sessa WC, Pritchard KA Jr. Ou J, et al. Among authors: sessa wc. Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H561-9. doi: 10.1152/ajpheart.00736.2003. Epub 2003 Oct 9. Am J Physiol Heart Circ Physiol. 2004. PMID: 14551044 Free article.

3

Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase.

Pritchard KA Jr, Ackerman AW, Gross ER, Stepp DW, Shi Y, Fontana JT, Baker JE, Sessa WC. Pritchard KA Jr, et al. Among authors: sessa wc. J Biol Chem. 2001 May 25;276(21):17621-4. doi: 10.1074/jbc.C100084200. Epub 2001 Mar 16. J Biol Chem. 2001. PMID: 11278264 Free article.

4

Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion.

Pritchard KA Jr, Groszek L, Smalley DM, Sessa WC, Wu M, Villalon P, Wolin MS, Stemerman MB. Pritchard KA Jr, et al. Among authors: sessa wc. Circ Res. 1995 Sep;77(3):510-8. doi: 10.1161/01.res.77.3.510. Circ Res. 1995. PMID: 7543827

5

Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.

Gratton JP, Fontana J, O'Connor DS, Garcia-Cardena G, McCabe TJ, Sessa WC. Gratton JP, et al. Among authors: sessa wc. J Biol Chem. 2000 Jul 21;275(29):22268-72. doi: 10.1074/jbc.M001644200. J Biol Chem. 2000. PMID: 10781589 Free article.

6

Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells.

Miao RQ, Fontana J, Fulton D, Lin MI, Harrison KD, Sessa WC. Miao RQ, et al. Among authors: sessa wc. Arterioscler Thromb Vasc Biol. 2008 Jan;28(1):105-11. doi: 10.1161/ATVBAHA.107.155499. Epub 2007 Nov 1. Arterioscler Thromb Vasc Biol. 2008. PMID: 17975117

7

Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release.

Fontana J, Fulton D, Chen Y, Fairchild TA, McCabe TJ, Fujita N, Tsuruo T, Sessa WC. Fontana J, et al. Among authors: sessa wc. Circ Res. 2002 May 3;90(8):866-73. doi: 10.1161/01.res.0000016837.26733.be. Circ Res. 2002. PMID: 11988487

8

Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production.

Lin MI, Fulton D, Babbitt R, Fleming I, Busse R, Pritchard KA Jr, Sessa WC. Lin MI, et al. Among authors: sessa wc. J Biol Chem. 2003 Nov 7;278(45):44719-26. doi: 10.1074/jbc.M302836200. Epub 2003 Sep 2. J Biol Chem. 2003. PMID: 12952971 Free article.

9

Vanadate is a potent activator of endothelial nitric-oxide synthase: evidence for the role of the serine/threonine kinase Akt and the 90-kDa heat shock protein.

Papapetropoulos A, Fulton D, Lin MI, Fontana J, McCabe TJ, Zoellner S, García-Cardeña G, Zhou Z, Gratton JP, Sessa WC. Papapetropoulos A, et al. Among authors: sessa wc. Mol Pharmacol. 2004 Feb;65(2):407-15. doi: 10.1124/mol.65.2.407. Mol Pharmacol. 2004. PMID: 14742683

10

Acidic hydrolysis as a mechanism for the cleavage of the Glu(298)-->Asp variant of human endothelial nitric-oxide synthase.

Fairchild TA, Fulton D, Fontana JT, Gratton JP, McCabe TJ, Sessa WC. Fairchild TA, et al. Among authors: sessa wc. J Biol Chem. 2001 Jul 13;276(28):26674-9. doi: 10.1074/jbc.M103647200. Epub 2001 Apr 30. J Biol Chem. 2001. PMID: 11331296 Free article.

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