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Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles.
Grefhorst A, Elzinga BM, Voshol PJ, Plösch T, Kok T, Bloks VW, van der Sluijs FH, Havekes LM, Romijn JA, Verkade HJ, Kuipers F. Grefhorst A, et al. Among authors: voshol pj. J Biol Chem. 2002 Sep 13;277(37):34182-90. doi: 10.1074/jbc.M204887200. Epub 2002 Jul 3. J Biol Chem. 2002. PMID: 12097330 Free article.
ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis.
Schaap FG, Rensen PC, Voshol PJ, Vrins C, van der Vliet HN, Chamuleau RA, Havekes LM, Groen AK, van Dijk KW. Schaap FG, et al. Among authors: voshol pj. J Biol Chem. 2004 Jul 2;279(27):27941-7. doi: 10.1074/jbc.M403240200. Epub 2004 Apr 16. J Biol Chem. 2004. PMID: 15090553 Free article.
112 results