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Exploration of the mutational landscape of cutaneous leiomyoma confirms FH as a driver gene and identifies targeting purine metabolism as a potential therapeutic strategy.
van der Weyden L, Del Castillo Velasco-Herrera M, Cheema S, Wong K, Boccacino JM, Vermes I, Offord V, Droop A, Jones DRA, Anderson E, Hardy C, de Saint Aubain N, Ferguson PM, Mogler C, Rajan N, Frew D, Harms PW, Billings SD, Schatton D, Segarra-Mondejar M, Arends MJ, Ferreira I, Brenn T, Frezza C, Adams DJ. van der Weyden L, et al. Among authors: adams dj. Br J Dermatol. 2024 Nov 7:ljae432. doi: 10.1093/bjd/ljae432. Online ahead of print. Br J Dermatol. 2024. PMID: 39506538 No abstract available.
Polyclonality overcomes fitness barriers in Apc-driven tumorigenesis.
Sadien ID, Adler S, Mehmed S, Bailey S, Sawle A, Couturier DL, Eldridge M, Adams DJ, Kemp R, Lourenço FC, Winton DJ. Sadien ID, et al. Among authors: adams dj. Nature. 2024 Oct;634(8036):1196-1203. doi: 10.1038/s41586-024-08053-0. Epub 2024 Oct 30. Nature. 2024. PMID: 39478206 Free PMC article.
Ancestry and somatic profile predict acral melanoma origin and prognosis.
Basurto-Lozada P, Vázquez-Cruz ME, Molina-Aguilar C, Jiang A, Deacon DC, Cerrato-Izaguirre D, Simonin-Wilmer I, Arriaga-González FG, Contreras-Ramírez KL, Dawson ET, Wong-Ramirez JRC, Ramos-Galguera JI, Álvarez-Cano A, García-Ortega DY, García-Salinas OI, Hidalgo-Miranda A, Cisneros-Villanueva M, Martínez-Said H, Arends MJ, Ferreira I, Tullett M, Olvera-León R, van der Weyden L, Del Castillo Velasco Herrera M, Roldán-Marín R, Vidaurri de la Cruz H, Tavares-de-la-Paz LA, Hinojosa-Ugarte D, Belote RL, Bishop DT, Díaz-Gay M, Alexandrov LB, Sánchez-Pérez Y, In GK, White RM, Possik PA, Judson-Torres RL, Adams DJ, Robles-Espinoza CD. Basurto-Lozada P, et al. Among authors: adams dj. medRxiv [Preprint]. 2024 Sep 23:2024.09.21.24313911. doi: 10.1101/2024.09.21.24313911. medRxiv. 2024. PMID: 39399030 Free PMC article. Preprint.
Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Elrick H, Peterson KA, Willis BJ, Lanza DG, Acar EF, Ryder EJ, Teboul L, Kasparek P, Birling MC, Adams DJ, Bradley A, Braun RE, Brown SD, Caulder A, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Duddy G, Gertsenstein M, Goodwin LO, Hérault Y, Lintott LG, Lloyd KCK, Lorenzo I, Mackenzie M, Mallon AM, McKerlie C, Parkinson H, Ramirez-Solis R, Seavitt JR, Sedlacek R, Skarnes WC, Smedley D, Wells S, White JK, Wood JA; International Mouse Phenotyping Consortium; Murray SA, Heaney JD, Nutter LMJ. Elrick H, et al. Among authors: adams dj. Sci Rep. 2024 Sep 30;14(1):22626. doi: 10.1038/s41598-024-72418-8. Sci Rep. 2024. PMID: 39349521 Free PMC article.
1,169 results