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Aggretin, a heterodimeric C-type lectin from Calloselasma rhodostoma (Malayan pit viper), stimulates platelets by binding to α2β1 integrin and glycoprotein Ib, activating Syk and phospholipase Cγ 2, but does not involve the glycoprotein VI/Fc receptor γ chain collagen receptor.
Navdaev A, Clemetson JM, Polgar J, Kehrel BE, Glauner M, Magnenat E, Wells TN, Clemetson KJ. Navdaev A, et al. Among authors: wells tn. J Biol Chem. 2001 Jun 15;276(24):20882-9. doi: 10.1074/jbc.M101585200. Epub 2001 Apr 3. J Biol Chem. 2001. PMID: 11287424 Free article.
Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin.
Hammouda MB, Riahi-Chebbi I, Souid S, Othman H, Aloui Z, Srairi-Abid N, Karoui H, Gasmi A, Magnenat EM, Wells TNC, Clemetson KJ, Rodríguez-López JN, Essafi-Benkhadir K. Hammouda MB, et al. Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):600-614. doi: 10.1016/j.bbagen.2017.11.019. Epub 2017 Nov 28. Biochim Biophys Acta Gen Subj. 2018. PMID: 29196192
Asp-49 is not an absolute prerequisite for the enzymic activity of low-M(r) phospholipases A2: purification, characterization and computer modelling of an enzymically active Ser-49 phospholipase A2, ecarpholin S, from the venom of Echis carinatus sochureki (saw-scaled viper).
Polgár J, Magnenat EM, Peitsch MC, Wells TN, Clemetson KJ. Polgár J, et al. Among authors: wells tn. Biochem J. 1996 Nov 1;319 ( Pt 3)(Pt 3):961-8. doi: 10.1042/bj3190961. Biochem J. 1996. PMID: 8921006 Free PMC article.
230 results