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Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene.
Constant P, Perez E, Malaga W, Lanéelle MA, Saurel O, Daffé M, Guilhot C. Constant P, et al. Among authors: daffe m. J Biol Chem. 2002 Oct 11;277(41):38148-58. doi: 10.1074/jbc.M206538200. Epub 2002 Jul 22. J Biol Chem. 2002. PMID: 12138124 Free article.
Tracking the putative biosynthetic precursors of oxygenated mycolates of Mycobacterium tuberculosis. Structural analysis of fatty acids of a mutant strain deviod of methoxy- and ketomycolates.
Dinadayala P, Laval F, Raynaud C, Lemassu A, Laneelle MA, Laneelle G, Daffe M. Dinadayala P, et al. Among authors: daffe m. J Biol Chem. 2003 Feb 28;278(9):7310-9. doi: 10.1074/jbc.M210501200. Epub 2002 Dec 6. J Biol Chem. 2003. PMID: 12473649 Free article.
Disruption of the mma4 gene (renamed hma) of Mycobacterium tuberculosis has yielded a mutant strain defective in the synthesis of both keto- and methoxymycolates, with an altered cell-wall permeability to small molecules and a decreased virulence in the mouse model of infection ( …
Disruption of the mma4 gene (renamed hma) of Mycobacterium tuberculosis has yielded a mutant strain defective in the synthesis of both keto- …
The acyl-AMP ligase FadD32 and AccD4-containing acyl-CoA carboxylase are required for the synthesis of mycolic acids and essential for mycobacterial growth: identification of the carboxylation product and determination of the acyl-CoA carboxylase components.
Portevin D, de Sousa-D'Auria C, Montrozier H, Houssin C, Stella A, Lanéelle MA, Bardou F, Guilhot C, Daffé M. Portevin D, et al. Among authors: daffe m. J Biol Chem. 2005 Mar 11;280(10):8862-74. doi: 10.1074/jbc.M408578200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632194 Free article.
p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis.
Stadthagen G, Korduláková J, Griffin R, Constant P, Bottová I, Barilone N, Gicquel B, Daffé M, Jackson M. Stadthagen G, et al. Among authors: daffe m. J Biol Chem. 2005 Dec 9;280(49):40699-706. doi: 10.1074/jbc.M508332200. Epub 2005 Oct 6. J Biol Chem. 2005. PMID: 16210318 Free article.
265 results