Riedl R - Search Results

1

Genomic effects of polyamide/DNA interactions on mRNA expression.

Supekova L, Pezacki JP, Su AI, Loweth CJ, Riedl R, Geierstanger B, Schultz PG, Wemmer DE. Supekova L, et al. Among authors: riedl r. Chem Biol. 2002 Jul;9(7):821-7. doi: 10.1016/s1074-5521(02)00174-6. Chem Biol. 2002. PMID: 12144926

2

Targeted Polypharmacology: Discovery of a Highly Potent Non-Hydroxamate Dual Matrix Metalloproteinase (MMP)-10/-13 Inhibitor.

Senn N, Ott M, Lanz J, Riedl R. Senn N, et al. Among authors: riedl r. J Med Chem. 2017 Dec 14;60(23):9585-9598. doi: 10.1021/acs.jmedchem.7b01001. Epub 2017 Oct 13. J Med Chem. 2017. PMID: 28953404

3

Cryo-EM structure of the prefusion state of canine distemper virus fusion protein ectodomain.

Kalbermatter D, Shrestha N, Gall FM, Wyss M, Riedl R, Plattet P, Fotiadis D. Kalbermatter D, et al. Among authors: riedl r. J Struct Biol X. 2020 Feb 29;4:100021. doi: 10.1016/j.yjsbx.2020.100021. eCollection 2020. J Struct Biol X. 2020. PMID: 32647825 Free PMC article.

4

Design and Structural Evolution of Matrix Metalloproteinase Inhibitors.

Fischer T, Senn N, Riedl R. Fischer T, et al. Among authors: riedl r. Chemistry. 2019 Jun 18;25(34):7960-7980. doi: 10.1002/chem.201805361. Epub 2019 May 2. Chemistry. 2019. PMID: 30720221 Review.

5

Merging allosteric and active site binding motifs: de novo generation of target selectivity and potency via natural-product-derived fragments.

Lanz J, Riedl R. Lanz J, et al. Among authors: riedl r. ChemMedChem. 2015 Mar;10(3):451-4. doi: 10.1002/cmdc.201402478. Epub 2014 Dec 8. ChemMedChem. 2015. PMID: 25487909 Free PMC article.

6

Challenges with matrix metalloproteinase inhibition and future drug discovery avenues.

Fischer T, Riedl R. Fischer T, et al. Among authors: riedl r. Expert Opin Drug Discov. 2021 Jan;16(1):75-88. doi: 10.1080/17460441.2020.1819235. Epub 2020 Sep 14. Expert Opin Drug Discov. 2021. PMID: 32921161 Review.

7

Inhibitory Antibodies Designed for Matrix Metalloproteinase Modulation.

Fischer T, Riedl R. Fischer T, et al. Among authors: riedl r. Molecules. 2019 Jun 18;24(12):2265. doi: 10.3390/molecules24122265. Molecules. 2019. PMID: 31216704 Free PMC article. Review.

8

Molecular Recognition of the Catalytic Zinc(II) Ion in MMP-13: Structure-Based Evolution of an Allosteric Inhibitor to Dual Binding Mode Inhibitors with Improved Lipophilic Ligand Efficiencies.

Fischer T, Riedl R. Fischer T, et al. Among authors: riedl r. Int J Mol Sci. 2016 Mar 1;17(3):314. doi: 10.3390/ijms17030314. Int J Mol Sci. 2016. PMID: 26938528 Free PMC article.

9

Development of a Non-Hydroxamate Dual Matrix Metalloproteinase (MMP)-7/-13 Inhibitor.

Fischer T, Riedl R. Fischer T, et al. Among authors: riedl r. Molecules. 2017 Sep 14;22(9):1548. doi: 10.3390/molecules22091548. Molecules. 2017. PMID: 32961647 Free PMC article.

10

Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor.

Fischer T, Riedl R. Fischer T, et al. Among authors: riedl r. ChemistryOpen. 2017 Jan 12;6(2):192-195. doi: 10.1002/open.201600158. eCollection 2017 Apr. ChemistryOpen. 2017. PMID: 28413749 Free PMC article.

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