Zhu Z - Search Results

1

Fab-scFv fusion protein: an efficient approach to production of bispecific antibody fragments.

Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. J Immunol Methods. 2002 Sep 15;267(2):213-26. doi: 10.1016/s0022-1759(02)00148-5. J Immunol Methods. 2002. PMID: 12165442

2

Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy.

Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. Int J Cancer. 2002 Jan 20;97(3):393-9. doi: 10.1002/ijc.1634. Int J Cancer. 2002. PMID: 11774295

3

Clinical development of angiogenesis inhibitors to vascular endothelial growth factor and its receptors as cancer therapeutics.

Zhu Z, Bohlen P, Witte L. Zhu Z, et al. Curr Cancer Drug Targets. 2002 Jun;2(2):135-56. doi: 10.2174/1568009023333881. Curr Cancer Drug Targets. 2002. PMID: 12188915 Review.

4

Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity.

Lu D, Shen J, Vil MD, Zhang H, Jimenez X, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. J Biol Chem. 2003 Oct 31;278(44):43496-507. doi: 10.1074/jbc.M307742200. Epub 2003 Aug 12. J Biol Chem. 2003. PMID: 12917408 Free article.

5

Di-diabody: a novel tetravalent bispecific antibody molecule by design.

Lu D, Jimenez X, Zhang H, Atkins A, Brennan L, Balderes P, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. J Immunol Methods. 2003 Aug;279(1-2):219-32. doi: 10.1016/s0022-1759(03)00251-5. J Immunol Methods. 2003. PMID: 12969563

6

Simultaneous blockade of both the epidermal growth factor receptor and the insulin-like growth factor receptor signaling pathways in cancer cells with a fully human recombinant bispecific antibody.

Lu D, Zhang H, Ludwig D, Persaud A, Jimenez X, Burtrum D, Balderes P, Liu M, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. J Biol Chem. 2004 Jan 23;279(4):2856-65. doi: 10.1074/jbc.M310132200. Epub 2003 Oct 23. J Biol Chem. 2004. PMID: 14576153 Free article.

7

The effect of variable domain orientation and arrangement on the antigen-binding activity of a recombinant human bispecific diabody.

Lu D, Jimenez X, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. Biochem Biophys Res Commun. 2004 May 28;318(2):507-13. doi: 10.1016/j.bbrc.2004.04.060. Biochem Biophys Res Commun. 2004. PMID: 15120630

8

Inhibition of both the autocrine and the paracrine growth of human leukemia with a fully human antibody directed against vascular endothelial growth factor receptor 2.

Zhang H, Li Y, Li H, Bassi R, Jimenez X, Witte L, Bohlen P, Hicklin D, Zhu Z. Zhang H, et al. Among authors: zhu z. Leuk Lymphoma. 2004 Sep;45(9):1887-97. doi: 10.1080/10428190410001712225. Leuk Lymphoma. 2004. PMID: 15223651

9

A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity.

Lu D, Zhang H, Koo H, Tonra J, Balderes P, Prewett M, Corcoran E, Mangalampalli V, Bassi R, Anselma D, Patel D, Kang X, Ludwig DL, Hicklin DJ, Bohlen P, Witte L, Zhu Z. Lu D, et al. Among authors: zhu z. J Biol Chem. 2005 May 20;280(20):19665-72. doi: 10.1074/jbc.M500815200. Epub 2005 Mar 9. J Biol Chem. 2005. PMID: 15757893 Free article.

10

A recombinant, fully human, bispecific antibody neutralizes the biological activities mediated by both vascular endothelial growth factor receptors 2 and 3.

Jimenez X, Lu D, Brennan L, Persaud K, Liu M, Miao H, Witte L, Zhu Z. Jimenez X, et al. Among authors: zhu z. Mol Cancer Ther. 2005 Mar;4(3):427-34. doi: 10.1158/1535-7163.MCT-04-0261. Mol Cancer Ther. 2005. PMID: 15767551

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