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Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity.
Karlsen AE, Rønn SG, Lindberg K, Johannesen J, Galsgaard ED, Pociot F, Nielsen JH, Mandrup-Poulsen T, Nerup J, Billestrup N. Karlsen AE, et al. Among authors: ronn sg. Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12191-6. doi: 10.1073/pnas.211445998. Epub 2001 Oct 2. Proc Natl Acad Sci U S A. 2001. PMID: 11593036 Free PMC article.
Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways.
Karlsen AE, Heding PE, Frobøse H, Rønn SG, Kruhøffer M, Orntoft TF, Darville M, Eizirik DL, Pociot F, Nerup J, Mandrup-Poulsen T, Billestrup N. Karlsen AE, et al. Among authors: ronn sg. Diabetologia. 2004 Nov;47(11):1998-2011. doi: 10.1007/s00125-004-1568-3. Epub 2004 Dec 2. Diabetologia. 2004. PMID: 15578154
Regulation of pancreatic beta-cell mass and proliferation by SOCS-3.
Lindberg K, Rønn SG, Tornehave D, Richter H, Hansen JA, Rømer J, Jackerott M, Billestrup N. Lindberg K, et al. Among authors: ronn sg. J Mol Endocrinol. 2005 Oct;35(2):231-43. doi: 10.1677/jme.1.01840. J Mol Endocrinol. 2005. PMID: 16216905
15 results