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Page 1
Pin1: a therapeutic target in Alzheimer neurodegeneration.
Hamdane M, Smet C, Sambo AV, Leroy A, Wieruszeski JM, Delobel P, Maurage CA, Ghestem A, Wintjens R, Bégard S, Sergeant N, Delacourte A, Horvath D, Landrieu I, Lippens G, Buée L. Hamdane M, et al. Among authors: ghestem a. J Mol Neurosci. 2002 Dec;19(3):275-87. doi: 10.1385/JMN:19:3:275. J Mol Neurosci. 2002. PMID: 12540053
Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
Vingtdeux V, Hamdane M, Gompel M, Bégard S, Drobecq H, Ghestem A, Grosjean ME, Kostanjevecki V, Grognet P, Vanmechelen E, Buée L, Delacourte A, Sergeant N. Vingtdeux V, et al. Among authors: ghestem a. Neurobiol Dis. 2005 Nov;20(2):625-37. doi: 10.1016/j.nbd.2005.05.004. Epub 2005 Jun 3. Neurobiol Dis. 2005. PMID: 15936948
Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.
Ando K, Dourlen P, Sambo AV, Bretteville A, Bélarbi K, Vingtdeux V, Eddarkaoui S, Drobecq H, Ghestem A, Bégard S, Demey-Thomas E, Melnyk P, Smet C, Lippens G, Maurage CA, Caillet-Boudin ML, Verdier Y, Vinh J, Landrieu I, Galas MC, Blum D, Hamdane M, Sergeant N, Buée L. Ando K, et al. Among authors: ghestem a. Neurobiol Aging. 2013 Mar;34(3):757-69. doi: 10.1016/j.neurobiolaging.2012.08.004. Epub 2012 Aug 25. Neurobiol Aging. 2013. PMID: 22926167
42 results