Gibbs EM - Search Results

1

Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

Ekstrom JL, Pauly TA, Carty MD, Soeller WC, Culp J, Danley DE, Hoover DJ, Treadway JL, Gibbs EM, Fletterick RJ, Day YS, Myszka DG, Rath VL. Ekstrom JL, et al. Among authors: gibbs em. Chem Biol. 2002 Aug;9(8):915-24. doi: 10.1016/s1074-5521(02)00186-2. Chem Biol. 2002. PMID: 12204691

2

5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.

Wright SW, Rath VL, Genereux PE, Hageman DL, Levy CB, McClure LD, McCoid SC, McPherson RK, Schelhorn TM, Wilder DE, Zavadoski WJ, Gibbs EM, Treadway JL. Wright SW, et al. Among authors: gibbs em. Bioorg Med Chem Lett. 2005 Jan 17;15(2):459-65. doi: 10.1016/j.bmcl.2004.10.048. Bioorg Med Chem Lett. 2005. PMID: 15603973

3

Establishment of correlation between in vitro enzyme binding potency and in vivo pharmacological activity: application to liver glycogen phosphorylase a inhibitors.

Yu LJ, Chen Y, Treadway JL, McPherson RK, McCoid SC, Gibbs EM, Hoover DJ. Yu LJ, et al. Among authors: gibbs em. J Pharmacol Exp Ther. 2006 Jun;317(3):1230-7. doi: 10.1124/jpet.105.100545. Epub 2006 Mar 14. J Pharmacol Exp Ther. 2006. PMID: 16537796

4

Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase.

Hoover DJ, Lefkowitz-Snow S, Burgess-Henry JL, Martin WH, Armento SJ, Stock IA, McPherson RK, Genereux PE, Gibbs EM, Treadway JL. Hoover DJ, et al. Among authors: gibbs em. J Med Chem. 1998 Jul 30;41(16):2934-8. doi: 10.1021/jm980264k. J Med Chem. 1998. PMID: 9685232 No abstract available.

5

Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.

Rath VL, Ammirati M, Danley DE, Ekstrom JL, Gibbs EM, Hynes TR, Mathiowetz AM, McPherson RK, Olson TV, Treadway JL, Hoover DJ. Rath VL, et al. Among authors: gibbs em. Chem Biol. 2000 Sep;7(9):677-82. doi: 10.1016/s1074-5521(00)00004-1. Chem Biol. 2000. PMID: 10980448

6

Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase.

Harwood HJ Jr, Petras SF, Hoover DJ, Mankowski DC, Soliman VF, Sugarman ED, Hulin B, Kwon Y, Gibbs EM, Mayne JT, Treadway JL. Harwood HJ Jr, et al. Among authors: gibbs em. J Lipid Res. 2005 Mar;46(3):547-63. doi: 10.1194/jlr.M400436-JLR200. Epub 2004 Dec 16. J Lipid Res. 2005. PMID: 15604516 Free article.

7

Endogenous effectors of human liver glycogen phosphorylase modulate effects of indole-site inhibitors.

Ercan-Fang N, Taylor MR, Treadway JL, Levy CB, Genereux PE, Gibbs EM, Rath VL, Kwon Y, Gannon MC, Nuttall FQ. Ercan-Fang N, et al. Among authors: gibbs em. Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E366-72. doi: 10.1152/ajpendo.00264.2004. Epub 2005 Mar 29. Am J Physiol Endocrinol Metab. 2005. PMID: 15797986 Free article.

8

Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia.

Johnson DE, Yamazaki H, Ward KM, Schmidt AW, Lebel WS, Treadway JL, Gibbs EM, Zawalich WS, Rollema H. Johnson DE, et al. Among authors: gibbs em. Diabetes. 2005 May;54(5):1552-8. doi: 10.2337/diabetes.54.5.1552. Diabetes. 2005. PMID: 15855345

9

Enhanced peripheral glucose utilization in transgenic mice expressing the human GLUT4 gene.

Treadway JL, Hargrove DM, Nardone NA, McPherson RK, Russo JF, Milici AJ, Stukenbrok HA, Gibbs EM, Stevenson RW, Pessin JE. Treadway JL, et al. Among authors: gibbs em. J Biol Chem. 1994 Nov 25;269(47):29956-61. J Biol Chem. 1994. PMID: 7961994 Free article.

10

Glucose transport-enhancing and hypoglycemic activity of 2-methyl-2-phenoxy-3-phenylpropanoic acids.

Sarges R, Hank RF, Blake JF, Bordner J, Bussolotti DL, Hargrove DM, Treadway JL, Gibbs EM. Sarges R, et al. Among authors: gibbs em. J Med Chem. 1996 Nov 22;39(24):4783-803. doi: 10.1021/jm950364f. J Med Chem. 1996. PMID: 8941393

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

118 results

Search Page

Filters