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Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.
Madani N, Schön A, Princiotto AM, Lalonde JM, Courter JR, Soeta T, Ng D, Wang L, Brower ET, Xiang SH, Kwon YD, Huang CC, Wyatt R, Kwong PD, Freire E, Smith AB 3rd, Sodroski J. Madani N, et al. Among authors: xiang sh. Structure. 2008 Nov 12;16(11):1689-701. doi: 10.1016/j.str.2008.09.005. Structure. 2008. PMID: 19000821 Free PMC article.
Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain.
Kassa A, Madani N, Schön A, Haim H, Finzi A, Xiang SH, Wang L, Princiotto A, Pancera M, Courter J, Smith AB 3rd, Freire E, Kwong PD, Sodroski J. Kassa A, et al. Among authors: xiang sh. J Virol. 2009 Sep;83(17):8364-78. doi: 10.1128/JVI.00594-09. Epub 2009 Jun 17. J Virol. 2009. PMID: 19535453 Free PMC article.
124 results