Qiu W - Search Results

1

A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity.

Qiu W, Campbell RL, Gangloff A, Dupuis P, Boivin RP, Tremblay MR, Poirier D, Lin SX. Qiu W, et al. FASEB J. 2002 Nov;16(13):1829-31. doi: 10.1096/fj.02-0026fje. Epub 2002 Sep 5. FASEB J. 2002. PMID: 12223444

2

Purification, crystallization and preliminary X-ray diffraction results of human 17beta-hydroxysteroid dehydrogenase type 5.

Zhou M, Qiu W, Chang HJ, Gangloff A, Lin SX. Zhou M, et al. Among authors: qiu w. Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):1048-50. doi: 10.1107/s0907444902005255. Epub 2002 May 29. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12037313

3

Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues.

Qiu W, Zhou M, Labrie F, Lin SX. Qiu W, et al. Mol Endocrinol. 2004 Jul;18(7):1798-807. doi: 10.1210/me.2004-0032. Epub 2004 Apr 15. Mol Endocrinol. 2004. PMID: 15087468

4

Estradiol-adenosine hybrid compounds designed to inhibit type 1 17beta-hydroxysteroid dehydrogenase.

Poirier D, Boivin RP, Tremblay MR, Bérubé M, Qiu W, Lin SX. Poirier D, et al. Among authors: qiu w. J Med Chem. 2005 Dec 29;48(26):8134-47. doi: 10.1021/jm058235e. J Med Chem. 2005. PMID: 16366595

5

Two non-reactive ternary complexes of estrogenic 17beta-hydroxysteroid dehydrogenase: crystallization and preliminary structural analysis.

Qiu W, Zhu DW, Azzi A, Campbell RL, Qi H, Poirier D, Lin SX. Qiu W, et al. J Steroid Biochem Mol Biol. 1999 Mar;68(5-6):239-44. doi: 10.1016/s0960-0760(99)00036-9. J Steroid Biochem Mol Biol. 1999. PMID: 10416839

6

Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.

Qiu W, Zhou M, Mazumdar M, Azzi A, Ghanmi D, Luu-The V, Labrie F, Lin SX. Qiu W, et al. J Biol Chem. 2007 Mar 16;282(11):8368-79. doi: 10.1074/jbc.M606784200. Epub 2006 Dec 13. J Biol Chem. 2007. PMID: 17166832 Free article.

7

Crystal structure of chloramphenicol acetyltransferase B2 encoded by the multiresistance transposon Tn2424.

Qiu W, Shi R, Lu ML, Zhou M, Roy PH, Lapointe J, Lin SX. Qiu W, et al. Proteins. 2004 Dec 1;57(4):858-61. doi: 10.1002/prot.20250. Proteins. 2004. PMID: 15390264 No abstract available.

8

Crystallization and preliminary X-ray diffraction analysis of the chloramphenicol acetyltransferase from Tn2424.

Zhou M, Lu ML, Qiu W, Campbell RL, Nahoum V, Lapointe J, Roy PH, Lin SX. Zhou M, et al. Among authors: qiu w. Acta Crystallogr D Biol Crystallogr. 2001 Feb;57(Pt 2):281-3. doi: 10.1107/s0907444900016802. Acta Crystallogr D Biol Crystallogr. 2001. PMID: 11173480

9

Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5.

Lin SX, Shi R, Qiu W, Azzi A, Zhu DW, Dabbagh HA, Zhou M. Lin SX, et al. Among authors: qiu w. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):38-46. doi: 10.1016/j.mce.2005.11.035. Epub 2006 Feb 15. Mol Cell Endocrinol. 2006. PMID: 16480815 Review.

10

Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.

Dufe VT, Qiu W, Müller IB, Hui R, Walter RD, Al-Karadaghi S. Dufe VT, et al. Among authors: qiu w. J Mol Biol. 2007 Oct 12;373(1):167-77. doi: 10.1016/j.jmb.2007.07.053. Epub 2007 Aug 2. J Mol Biol. 2007. PMID: 17822713

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