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The conserved glutamate residue adjacent to the Walker-B motif is the catalytic base for ATP hydrolysis in the ATP-binding cassette transporter BmrA.
Orelle C, Dalmas O, Gros P, Di Pietro A, Jault JM. Orelle C, et al. Among authors: di pietro a. J Biol Chem. 2003 Nov 21;278(47):47002-8. doi: 10.1074/jbc.M308268200. Epub 2003 Sep 10. J Biol Chem. 2003. PMID: 12968023 Free article.
In particular, it has been postulated that ATP hydrolysis proceeds via an acid-base mechanism catalyzed by the Glu residue adjacent to the Walker-B motif (Geourjon, C., Orelle, C., Steinfels, E., Blanchet, C., Deleage, G., Di Pietro, A., and Jault, J. M. (200 …
In particular, it has been postulated that ATP hydrolysis proceeds via an acid-base mechanism catalyzed by the Glu residue adjacent to the W …
520 results