Cottrell IF - Search Results

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Practical asymmetric synthesis of aprepitant, a potent human NK-1 receptor antagonist, via a stereoselective Lewis acid-catalyzed trans acetalization reaction.

Zhao MM, McNamara JM, Ho GJ, Emerson KM, Song ZJ, Tschaen DM, Brands KM, Dolling UH, Grabowski EJ, Reider PJ, Cottrell IF, Ashwood MS, Bishop BC. Zhao MM, et al. Among authors: cottrell if. J Org Chem. 2002 Sep 20;67(19):6743-7. doi: 10.1021/jo0203793. J Org Chem. 2002. PMID: 12227806

Efficient one-pot synthesis of the 2-aminocarbonylpyrrolidin-4-ylthio-containing side chain of the new broad-spectrum carbapenem antibiotic ertapenem.

Brands KM, Jobson RB, Conrad KM, Williams JM, Pipik B, Cameron M, Davies AJ, Houghton PG, Ashwood MS, Cottrell IF, Reamer RA, Kennedy DJ, Dolling UH, Reider PJ. Brands KM, et al. Among authors: cottrell if. J Org Chem. 2002 Jul 12;67(14):4771-6. doi: 10.1021/jo011170c. J Org Chem. 2002. PMID: 12098287

A double ring closing metathesis reaction in the rapid, enantioselective synthesis of NK-1 receptor antagonists.

Wallace DJ, Goodman JM, Kennedy DJ, Davies AJ, Cowden CJ, Ashwood MS, Cottrell IF, Dolling UH, Reider PJ. Wallace DJ, et al. Among authors: cottrell if. Org Lett. 2001 Mar 8;3(5):671-4. doi: 10.1021/ol006958g. Org Lett. 2001. PMID: 11259033

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