Lessnick SL - Search Results

1

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor.

Widlund HR, Horstmann MA, Price ER, Cui J, Lessnick SL, Wu M, He X, Fisher DE. Widlund HR, et al. Among authors: lessnick sl. J Cell Biol. 2002 Sep 16;158(6):1079-87. doi: 10.1083/jcb.200202049. Epub 2002 Sep 16. J Cell Biol. 2002. PMID: 12235125 Free PMC article.

2

Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers.

Davis IJ, Kim JJ, Ozsolak F, Widlund HR, Rozenblatt-Rosen O, Granter SR, Du J, Fletcher JA, Denny CT, Lessnick SL, Linehan WM, Kung AL, Fisher DE. Davis IJ, et al. Among authors: lessnick sl. Cancer Cell. 2006 Jun;9(6):473-84. doi: 10.1016/j.ccr.2006.04.021. Cancer Cell. 2006. PMID: 16766266 Free article.

3

The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts.

Lessnick SL, Dacwag CS, Golub TR. Lessnick SL, et al. Cancer Cell. 2002 May;1(4):393-401. doi: 10.1016/s1535-6108(02)00056-9. Cancer Cell. 2002. PMID: 12086853 Free article.

4

The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.

Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J. Gozani O, et al. Among authors: lessnick sl. Cell. 2003 Jul 11;114(1):99-111. doi: 10.1016/s0092-8674(03)00480-x. Cell. 2003. PMID: 12859901 Free article.

5

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma.

Chaturvedi A, Hoffman LM, Jensen CC, Lin YC, Grossmann AH, Randall RL, Lessnick SL, Welm AL, Beckerle MC. Chaturvedi A, et al. Among authors: lessnick sl. Mol Biol Cell. 2014 Sep 15;25(18):2695-709. doi: 10.1091/mbc.E14-01-0007. Epub 2014 Jul 23. Mol Biol Cell. 2014. PMID: 25057021 Free PMC article.

6

Expression of EWS-ETS fusions in NIH3T3 cells reveals significant differences to Ewing's sarcoma.

Braunreiter CL, Hancock JD, Coffin CM, Boucher KM, Lessnick SL. Braunreiter CL, et al. Among authors: lessnick sl. Cell Cycle. 2006 Dec;5(23):2753-9. doi: 10.4161/cc.5.23.3505. Epub 2006 Dec 1. Cell Cycle. 2006. PMID: 17172842

7

Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.

Stegmaier K, Wong JS, Ross KN, Chow KT, Peck D, Wright RD, Lessnick SL, Kung AL, Golub TR. Stegmaier K, et al. Among authors: lessnick sl. PLoS Med. 2007 Apr;4(4):e122. doi: 10.1371/journal.pmed.0040122. PLoS Med. 2007. PMID: 17425403 Free PMC article.

8

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells.

Dolma S, Lessnick SL, Hahn WC, Stockwell BR. Dolma S, et al. Among authors: lessnick sl. Cancer Cell. 2003 Mar;3(3):285-96. doi: 10.1016/s1535-6108(03)00050-3. Cancer Cell. 2003. PMID: 12676586 Free article.

9

A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature.

Hancock JD, Lessnick SL. Hancock JD, et al. Among authors: lessnick sl. Cell Cycle. 2008 Jan 15;7(2):250-6. doi: 10.4161/cc.7.2.5229. Epub 2007 Oct 30. Cell Cycle. 2008. PMID: 18256529

10

EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.

Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR. Gorthi A, et al. Among authors: lessnick sl. Nature. 2018 Mar 15;555(7696):387-391. doi: 10.1038/nature25748. Epub 2018 Mar 7. Nature. 2018. PMID: 29513652 Free PMC article.

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