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The psychological impact of MND on patients and carers.
Goldstein LH, Adamson M, Jeffrey L, Down K, Barby T, Wilson C, Leigh PN. Goldstein LH, et al. Among authors: down k. J Neurol Sci. 1998 Oct;160 Suppl 1:S114-21. doi: 10.1016/s0022-510x(98)00209-3. J Neurol Sci. 1998. PMID: 9851660
Covalent targeting of non-cysteine residues in PI4KIIIβ.
Cosgrove B, Grant EK, Bertrand S, Down KD, Somers DO, P Evans J, Tomkinson NCO, Barker MD. Cosgrove B, et al. Among authors: down kd. RSC Chem Biol. 2023 Oct 17;4(12):1111-1122. doi: 10.1039/d3cb00142c. eCollection 2023 Nov 29. RSC Chem Biol. 2023. PMID: 38033723 Free PMC article.
Discovery of GSK251: A Highly Potent, Highly Selective, Orally Bioavailable Inhibitor of PI3Kδ with a Novel Binding Mode.
Down K, Amour A, Anderson NA, Barton N, Campos S, Cannons EP, Clissold C, Convery MA, Coward JJ, Doyle K, Duempelfeld B, Edwards CD, Goldsmith MD, Krause J, Mallett DN, McGonagle GA, Patel VK, Rowedder J, Rowland P, Sharpe A, Sriskantharajah S, Thomas DA, Thomson DW, Uddin S, Hamblin JN, Hessel EM. Down K, et al. J Med Chem. 2021 Sep 23;64(18):13780-13792. doi: 10.1021/acs.jmedchem.1c01102. Epub 2021 Sep 11. J Med Chem. 2021. PMID: 34510892
26 results