Butters TD - Search Results

1

An inducible mouse model of late onset Tay-Sachs disease.

Jeyakumar M, Smith D, Eliott-Smith E, Cortina-Borja M, Reinkensmeier G, Butters TD, Lemm T, Sandhoff K, Perry VH, Dwek RA, Platt FM. Jeyakumar M, et al. Among authors: butters td. Neurobiol Dis. 2002 Aug;10(3):201-10. doi: 10.1006/nbdi.2002.0511. Neurobiol Dis. 2002. PMID: 12270683

2

Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease.

Andersson U, Smith D, Jeyakumar M, Butters TD, Borja MC, Dwek RA, Platt FM. Andersson U, et al. Among authors: butters td. Neurobiol Dis. 2004 Aug;16(3):506-15. doi: 10.1016/j.nbd.2004.04.012. Neurobiol Dis. 2004. PMID: 15262262

3

Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin.

Platt FM, Neises GR, Reinkensmeier G, Townsend MJ, Perry VH, Proia RL, Winchester B, Dwek RA, Butters TD. Platt FM, et al. Among authors: butters td. Science. 1997 Apr 18;276(5311):428-31. doi: 10.1126/science.276.5311.428. Science. 1997. PMID: 9103204

4

Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin.

Jeyakumar M, Butters TD, Cortina-Borja M, Hunnam V, Proia RL, Perry VH, Dwek RA, Platt FM. Jeyakumar M, et al. Among authors: butters td. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6388-93. doi: 10.1073/pnas.96.11.6388. Proc Natl Acad Sci U S A. 1999. PMID: 10339597 Free PMC article.

5

Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis.

Jeyakumar M, Butters TD, Dwek RA, Platt FM. Jeyakumar M, et al. Among authors: butters td. Neuropathol Appl Neurobiol. 2002 Oct;28(5):343-57. doi: 10.1046/j.1365-2990.2002.00422.x. Neuropathol Appl Neurobiol. 2002. PMID: 12366816 Review.

6

Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis.

Jeyakumar M, Thomas R, Elliot-Smith E, Smith DA, van der Spoel AC, d'Azzo A, Perry VH, Butters TD, Dwek RA, Platt FM. Jeyakumar M, et al. Among authors: butters td. Brain. 2003 Apr;126(Pt 4):974-87. doi: 10.1093/brain/awg089. Brain. 2003. PMID: 12615653

7

Targeting glycosylation as a therapeutic approach.

Dwek RA, Butters TD, Platt FM, Zitzmann N. Dwek RA, et al. Among authors: butters td. Nat Rev Drug Discov. 2002 Jan;1(1):65-75. doi: 10.1038/nrd708. Nat Rev Drug Discov. 2002. PMID: 12119611 Review.

8

Reversible infertility in male mice after oral administration of alkylated imino sugars: a nonhormonal approach to male contraception.

van der Spoel AC, Jeyakumar M, Butters TD, Charlton HM, Moore HD, Dwek RA, Platt FM. van der Spoel AC, et al. Among authors: butters td. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17173-8. doi: 10.1073/pnas.262586099. Epub 2002 Dec 11. Proc Natl Acad Sci U S A. 2002. PMID: 12477936 Free PMC article.

9

Therapeutic applications of imino sugars in lysosomal storage disorders.

Butters TD, Dwek RA, Platt FM. Butters TD, et al. Curr Top Med Chem. 2003;3(5):561-74. doi: 10.2174/1568026033452483. Curr Top Med Chem. 2003. PMID: 12570866 Review.

10

Substrate reduction therapy in mouse models of the glycosphingolipidoses.

Platt FM, Jeyakumar M, Andersson U, Heare T, Dwek RA, Butters TD. Platt FM, et al. Among authors: butters td. Philos Trans R Soc Lond B Biol Sci. 2003 May 29;358(1433):947-54. doi: 10.1098/rstb.2003.1279. Philos Trans R Soc Lond B Biol Sci. 2003. PMID: 12803928 Free PMC article. Review.

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