Onuffer JJ - Search Results

1

Chemokines, chemokine receptors and small-molecule antagonists: recent developments.

Onuffer JJ, Horuk R. Onuffer JJ, et al. Trends Pharmacol Sci. 2002 Oct;23(10):459-67. doi: 10.1016/s0165-6147(02)02064-3. Trends Pharmacol Sci. 2002. PMID: 12368070 Review.

2

Structure function differences in nonpeptide CCR1 antagonists for human and mouse CCR1.

Onuffer J, McCarrick MA, Dunning L, Liang M, Rosser M, Wei GP, Ng H, Horuk R. Onuffer J, et al. J Immunol. 2003 Feb 15;170(4):1910-6. doi: 10.4049/jimmunol.170.4.1910. J Immunol. 2003. PMID: 12574358

3

A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.

Anders HJ, Vielhauer V, Frink M, Linde Y, Cohen CD, Blattner SM, Kretzler M, Strutz F, Mack M, Gröne HJ, Onuffer J, Horuk R, Nelson PJ, Schlöndorff D. Anders HJ, et al. J Clin Invest. 2002 Jan;109(2):251-9. doi: 10.1172/JCI14040. J Clin Invest. 2002. PMID: 11805137 Free PMC article.

4

CCR5 receptor antagonists: discovery and SAR study of guanylhydrazone derivatives.

Wei RG, Arnaiz DO, Chou YL, Davey D, Dunning L, Lee W, Lu SF, Onuffer J, Ye B, Phillips G. Wei RG, et al. Bioorg Med Chem Lett. 2007 Jan 1;17(1):231-4. doi: 10.1016/j.bmcl.2006.09.052. Epub 2006 Nov 1. Bioorg Med Chem Lett. 2007. PMID: 17081751

5

CCR5 receptor antagonists: discovery and SAR of novel 4-hydroxypiperidine derivatives.

Lu SF, Chen B, Davey D, Dunning L, Jaroch S, May K, Onuffer J, Phillips G, Subramanyam B, Tseng JL, Wei RG, Wei M, Ye B. Lu SF, et al. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1883-7. doi: 10.1016/j.bmcl.2007.01.050. Epub 2007 Jan 25. Bioorg Med Chem Lett. 2007. PMID: 17314043

6

The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental autoimmune encephalomyelitis in rodents.

Dinter H, Tse J, Halks-Miller M, Asarnow D, Onuffer J, Faulds D, Mitrovic B, Kirsch G, Laurent H, Esperling P, Seidelmann D, Ottow E, Schneider H, Tuohy VK, Wachtel H, Perez HD. Dinter H, et al. J Neuroimmunol. 2000 Aug 1;108(1-2):136-46. doi: 10.1016/s0165-5728(00)00265-4. J Neuroimmunol. 2000. PMID: 10900347

7

Phosphodiesterase type IV inhibitors in the treatment of multiple sclerosis.

Dinter H, Onuffer J, Faulds D, Perez HD. Dinter H, et al. J Mol Med (Berl). 1997 Feb;75(2):95-102. doi: 10.1007/s001090050094. J Mol Med (Berl). 1997. PMID: 9083927

8

Actin dynamics rapidly reset chemoattractant receptor sensitivity following adaptation in neutrophils.

Dandekar SN, Park JS, Peng GE, Onuffer JJ, Lim WA, Weiner OD. Dandekar SN, et al. Among authors: onuffer jj. Philos Trans R Soc Lond B Biol Sci. 2013 Sep 23;368(1629):20130008. doi: 10.1098/rstb.2013.0008. Print 2013. Philos Trans R Soc Lond B Biol Sci. 2013. PMID: 24062580 Free PMC article.

9

Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells.

Wei P, Wong WW, Park JS, Corcoran EE, Peisajovich SG, Onuffer JJ, Weiss A, Lim WA. Wei P, et al. Among authors: onuffer jj. Nature. 2012 Aug 16;488(7411):384-8. doi: 10.1038/nature11259. Nature. 2012. PMID: 22820255 Free PMC article.

10

Redesign of the substrate specificity of Escherichia coli aspartate aminotransferase to that of Escherichia coli tyrosine aminotransferase by homology modeling and site-directed mutagenesis.

Onuffer JJ, Kirsch JF. Onuffer JJ, et al. Protein Sci. 1995 Sep;4(9):1750-7. doi: 10.1002/pro.5560040910. Protein Sci. 1995. PMID: 8528073 Free PMC article.

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