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Page 1
Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice.
Wilson SM, Householder DB, Coppola V, Tessarollo L, Fritzsch B, Lee EC, Goss D, Carlson GA, Copeland NG, Jenkins NA. Wilson SM, et al. Among authors: householder db. Genomics. 2001 Jun 1;74(2):228-33. doi: 10.1006/geno.2001.6554. Genomics. 2001. PMID: 11386759
Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.
Szabova L, Bupp S, Kamal M, Householder DB, Hernandez L, Schlomer JJ, Baran ML, Yi M, Stephens RM, Annunziata CM, Martin PL, Van Dyke TA, Weaver Ohler Z, Difilippantonio S. Szabova L, et al. Among authors: householder db. PLoS One. 2014 Apr 18;9(4):e95649. doi: 10.1371/journal.pone.0095649. eCollection 2014. PLoS One. 2014. PMID: 24748377 Free PMC article.
A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors.
El Meskini R, Iacovelli AJ, Kulaga A, Gumprecht M, Martin PL, Baran M, Householder DB, Van Dyke T, Weaver Ohler Z. El Meskini R, et al. Among authors: householder db. Dis Model Mech. 2015 Jan;8(1):45-56. doi: 10.1242/dmm.018168. Epub 2014 Nov 27. Dis Model Mech. 2015. PMID: 25431423 Free PMC article.
Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation of Rb family proteins.
Szabova L, Gordon MB, Lu L, Pate N, Bassel L, Iacovelli AJ, Karim B, Homan PJ, Householder DB, Guerin TM, Burkett S, Day AM, Custer W, Weaver Ohler Z. Szabova L, et al. Among authors: householder db. Breast Cancer Res. 2022 Nov 4;24(1):75. doi: 10.1186/s13058-022-01566-4. Breast Cancer Res. 2022. PMID: 36333737 Free PMC article.
Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response.
Lee U, Szabova L, Collins VJ, Gordon M, Johnson K, Householder D, Jorgensen S, Lu L, Bassel L, Elloumi F, Peer CJ, Nelson AE, Varriano S, Varma S, Roberts RD, Ohler ZW, Figg WD, Sharan SK, Pommier Y, Heske CM. Lee U, et al. Front Cell Dev Biol. 2024 Oct 24;12:1462840. doi: 10.3389/fcell.2024.1462840. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 39512899 Free PMC article.