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Three weekly injections (TWI) of low-dose growth hormone (GH) restore low normal circulating IGF-I concentrations and reverse cardiac abnormalities associated with adult onset GH deficiency (GHD).
Pincelli AI, Bragato R, Scacchi M, Branzi G, Osculati G, Viarengo R, Leonetti G, Cavagnini F. Pincelli AI, et al. Among authors: viarengo r. J Endocrinol Invest. 2003 May;26(5):420-8. doi: 10.1007/BF03345197. J Endocrinol Invest. 2003. PMID: 12906369 Clinical Trial.