Huang M - Search Results

1

Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin.

Nimmanapalli R, O'Bryan E, Huang M, Bali P, Burnette PK, Loughran T, Tepperberg J, Jove R, Bhalla K. Nimmanapalli R, et al. Among authors: huang m. Cancer Res. 2002 Oct 15;62(20):5761-9. Cancer Res. 2002. PMID: 12384536

2

Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells.

Huang M, Dorsey JF, Epling-Burnette PK, Nimmanapalli R, Landowski TH, Mora LB, Niu G, Sinibaldi D, Bai F, Kraker A, Yu H, Moscinski L, Wei S, Djeu J, Dalton WS, Bhalla K, Loughran TP, Wu J, Jove R. Huang M, et al. Oncogene. 2002 Dec 12;21(57):8804-16. doi: 10.1038/sj.onc.1206028. Oncogene. 2002. PMID: 12483533

3

Flavopiridol down-regulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis.

Wittmann S, Bali P, Donapaty S, Nimmanapalli R, Guo F, Yamaguchi H, Huang M, Jove R, Wang HG, Bhalla K. Wittmann S, et al. Among authors: huang m. Cancer Res. 2003 Jan 1;63(1):93-9. Cancer Res. 2003. PMID: 12517783

4

Interleukin-3 protects Bcr-Abl-transformed hematopoietic progenitor cells from apoptosis induced by Bcr-Abl tyrosine kinase inhibitors.

Dorsey JF, Cunnick JM, Lanehart R, Huang M, Kraker AJ, Bhalla KN, Jove R, Wu J. Dorsey JF, et al. Among authors: huang m. Leukemia. 2002 Sep;16(9):1589-95. doi: 10.1038/sj.leu.2402678. Leukemia. 2002. PMID: 12200668

5

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth.

Niu G, Bowman T, Huang M, Shivers S, Reintgen D, Daud A, Chang A, Kraker A, Jove R, Yu H. Niu G, et al. Among authors: huang m. Oncogene. 2002 Oct 10;21(46):7001-10. doi: 10.1038/sj.onc.1205859. Oncogene. 2002. PMID: 12370822

6

Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change.

Rahmani M, Reese E, Dai Y, Bauer C, Kramer LB, Huang M, Jove R, Dent P, Grant S. Rahmani M, et al. Among authors: huang m. Mol Pharmacol. 2005 Apr;67(4):1166-76. doi: 10.1124/mol.104.007831. Epub 2004 Dec 29. Mol Pharmacol. 2005. PMID: 15625278

7

Beta1 integrin adhesion enhances IL-6-mediated STAT3 signaling in myeloma cells: implications for microenvironment influence on tumor survival and proliferation.

Shain KH, Yarde DN, Meads MB, Huang M, Jove R, Hazlehurst LA, Dalton WS. Shain KH, et al. Among authors: huang m. Cancer Res. 2009 Feb 1;69(3):1009-15. doi: 10.1158/0008-5472.CAN-08-2419. Epub 2009 Jan 20. Cancer Res. 2009. PMID: 19155309 Free PMC article.

8

Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest.

Niu G, Shain KH, Huang M, Ravi R, Bedi A, Dalton WS, Jove R, Yu H. Niu G, et al. Among authors: huang m. Cancer Res. 2001 Apr 15;61(8):3276-80. Cancer Res. 2001. PMID: 11309279

9

Inhibition of JAK kinase activity enhances Fas-mediated apoptosis but reduces cytotoxic activity of topoisomerase II inhibitors in U266 myeloma cells.

Oshiro MM, Landowski TH, Catlett-Falcone R, Hazlehurst LA, Huang M, Jove R, Dalton WS. Oshiro MM, et al. Among authors: huang m. Clin Cancer Res. 2001 Dec;7(12):4262-71. Clin Cancer Res. 2001. PMID: 11751528

10

Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.

Nefedova Y, Huang M, Kusmartsev S, Bhattacharya R, Cheng P, Salup R, Jove R, Gabrilovich D. Nefedova Y, et al. Among authors: huang m. J Immunol. 2004 Jan 1;172(1):464-74. doi: 10.4049/jimmunol.172.1.464. J Immunol. 2004. PMID: 14688356

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