Chamberlain PP - Search Results

1

Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors.

Ren J, Bird LE, Chamberlain PP, Stewart-Jones GB, Stuart DI, Stammers DK. Ren J, et al. Among authors: chamberlain pp. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14410-5. doi: 10.1073/pnas.222366699. Epub 2002 Oct 17. Proc Natl Acad Sci U S A. 2002. PMID: 12386343 Free PMC article.

2

Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.

Ren J, Nichols CE, Stamp A, Chamberlain PP, Ferris R, Weaver KL, Short SA, Stammers DK. Ren J, et al. Among authors: chamberlain pp. FEBS J. 2006 Aug;273(16):3850-60. doi: 10.1111/j.1742-4658.2006.05392.x. FEBS J. 2006. PMID: 16911530 Free article.

3

Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.

Chamberlain PP, Ren J, Nichols CE, Douglas L, Lennerstrand J, Larder BA, Stuart DI, Stammers DK. Chamberlain PP, et al. J Virol. 2002 Oct;76(19):10015-9. doi: 10.1128/jvi.76.19.10015-10019.2002. J Virol. 2002. PMID: 12208978 Free PMC article.

4

Crystal structures of HIV-1 reverse transcriptases mutated at codons 100, 106 and 108 and mechanisms of resistance to non-nucleoside inhibitors.

Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Stammers DK. Ren J, et al. Among authors: chamberlain pp. J Mol Biol. 2004 Feb 20;336(3):569-78. doi: 10.1016/j.jmb.2003.12.055. J Mol Biol. 2004. PMID: 15095972

5

Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.

Ren J, Nichols C, Bird L, Chamberlain P, Weaver K, Short S, Stuart DI, Stammers DK. Ren J, et al. J Mol Biol. 2001 Sep 28;312(4):795-805. doi: 10.1006/jmbi.2001.4988. J Mol Biol. 2001. PMID: 11575933

6

Molecular glue CELMoD compounds are regulators of cereblon conformation.

Watson ER, Novick S, Matyskiela ME, Chamberlain PP, H de la Peña A, Zhu J, Tran E, Griffin PR, Wertz IE, Lander GC. Watson ER, et al. Among authors: chamberlain pp. Science. 2022 Nov 4;378(6619):549-553. doi: 10.1126/science.add7574. Epub 2022 Nov 3. Science. 2022. PMID: 36378961 Free PMC article.

7

Structure of the human marker of self 5-transmembrane receptor CD47.

Fenalti G, Villanueva N, Griffith M, Pagarigan B, Lakkaraju SK, Huang RY, Ladygina N, Sharma A, Mikolon D, Abbasian M, Johnson J, Hadjivassiliou H, Zhu D, Chamberlain PP, Cho H, Hariharan K. Fenalti G, et al. Among authors: chamberlain pp. Nat Commun. 2021 Sep 1;12(1):5218. doi: 10.1038/s41467-021-25475-w. Nat Commun. 2021. PMID: 34471125 Free PMC article.

8

Profiling CELMoD-Mediated Degradation of Cereblon Neosubstrates.

Thompson JW, Clayton T, Khambatta G, Bateman LA, Carroll CW, Chamberlain PP, Matyskiela ME. Thompson JW, et al. Among authors: chamberlain pp. Methods Mol Biol. 2021;2365:283-300. doi: 10.1007/978-1-0716-1665-9_15. Methods Mol Biol. 2021. PMID: 34432250

9

Avadomide induces degradation of ZMYM2 fusion oncoproteins in hematologic malignancies.

Renneville A, Gasser JA, Grinshpun DE, Jean Beltran PM, Udeshi ND, Matyskiela ME, Clayton T, McConkey M, Viswanathan K, Tepper A, Guirguis AA, Sellar RS, Cotteret S, Marzac C, Saada V, De Botton S, Kiladjian JJ, Cayuela JM, Rolfe M, Chamberlain PP, Carr SA, Ebert BL. Renneville A, et al. Among authors: chamberlain pp. Blood Cancer Discov. 2021 May;2(3):250-265. doi: 10.1158/2643-3230.BCD-20-0105. Epub 2021 Mar 10. Blood Cancer Discov. 2021. PMID: 34027417 Free PMC article.

10

Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma.

Gooding S, Ansari-Pour N, Towfic F, Ortiz Estévez M, Chamberlain PP, Tsai KT, Flynt E, Hirst M, Rozelle D, Dhiman P, Neri P, Ramasamy K, Bahlis N, Vyas P, Thakurta A. Gooding S, et al. Among authors: chamberlain pp. Blood. 2021 Jan 14;137(2):232-237. doi: 10.1182/blood.2020007081. Blood. 2021. PMID: 33443552 Free PMC article.

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