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Specific human granulocyte-macrophage colony-stimulating factor antagonists.
Hercus TR, Bagley CJ, Cambareri B, Dottore M, Woodcock JM, Vadas MA, Shannon MF, Lopez AF. Hercus TR, et al. Among authors: bagley cj. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5838-42. doi: 10.1073/pnas.91.13.5838. Proc Natl Acad Sci U S A. 1994. PMID: 8016076 Free PMC article.
A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all three ligands.
Woodcock JM, Bagley CJ, Zacharakis B, Lopez AF. Woodcock JM, et al. Among authors: bagley cj. J Biol Chem. 1996 Oct 18;271(42):25999-6006. doi: 10.1074/jbc.271.42.25999. J Biol Chem. 1996. PMID: 8824238 Free article.
Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors.
Stomski FC, Woodcock JM, Zacharakis B, Bagley CJ, Sun Q, Lopez AF. Stomski FC, et al. Among authors: bagley cj. J Biol Chem. 1998 Jan 9;273(2):1192-9. doi: 10.1074/jbc.273.2.1192. J Biol Chem. 1998. PMID: 9422786 Free article.
59 results