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Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lines.
Ling YH, Li T, Yuan Z, Haigentz M Jr, Weber TK, Perez-Soler R. Ling YH, et al. Mol Pharmacol. 2007 Aug;72(2):248-58. doi: 10.1124/mol.107.034827. Epub 2007 Apr 24. Mol Pharmacol. 2007. Retraction in: Mol Pharmacol. 2015 Aug;88(2):390. doi: 10.1124/mol.115.08er15a PMID: 17456787 Retracted.
Randomized Phase 2 Trial of Pharmacodynamic Separation of Pemetrexed and Intercalated Erlotinib Versus Pemetrexed Alone for Advanced Nonsquamous, Non-small-cell Lung Cancer.
Li T, Piperdi B, Walsh WV, Kim M, Beckett LA, Gucalp R, Haigentz M Jr, Bathini VG, Wen H, Zhou K, Pasquinelli PB, Gajavelli S, Sreedhara M, Xie X, Lara PN Jr, Gandara DR, Perez-Soler R. Li T, et al. Clin Lung Cancer. 2017 Jan;18(1):60-67. doi: 10.1016/j.cllc.2016.10.003. Epub 2016 Oct 28. Clin Lung Cancer. 2017. PMID: 27919627 Free PMC article. Clinical Trial.
Emerging treatment for advanced lung cancer with EGFR mutation.
Inal C, Yilmaz E, Piperdi B, Perez-Soler R, Cheng H. Inal C, et al. Expert Opin Emerg Drugs. 2015;20(4):597-612. doi: 10.1517/14728214.2015.1058778. Epub 2015 Jul 8. Expert Opin Emerg Drugs. 2015. PMID: 26153235 Review.
206 results