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Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK1/2. Amplification of ROS and Ras in systemic sclerosis fibroblasts.
Svegliati S, Cancello R, Sambo P, Luchetti M, Paroncini P, Orlandini G, Discepoli G, Paterno R, Santillo M, Cuozzo C, Cassano S, Avvedimento EV, Gabrielli A. Svegliati S, et al. Among authors: paroncini p. J Biol Chem. 2005 Oct 28;280(43):36474-82. doi: 10.1074/jbc.M502851200. Epub 2005 Aug 4. J Biol Chem. 2005. PMID: 16081426 Free article.
Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway.
Sambo P, Baroni SS, Luchetti M, Paroncini P, Dusi S, Orlandini G, Gabrielli A. Sambo P, et al. Among authors: paroncini p. Arthritis Rheum. 2001 Nov;44(11):2653-64. doi: 10.1002/1529-0131(200111)44:11<2653::aid-art445>3.0.co;2-1. Arthritis Rheum. 2001. PMID: 11710721 Free article.
Scleroderma fibroblasts constitutively express the long pentraxin PTX3.
Luchetti MM, Sambo P, Majlingová P, Svegliati Baroni S, Peri G, Paroncini P, Introna M, Stoppacciaro A, Mantovani A, Gabrielli A. Luchetti MM, et al. Among authors: paroncini p. Clin Exp Rheumatol. 2004 Jan-Feb;22(3 Suppl 33):S66-72. Clin Exp Rheumatol. 2004. PMID: 15344601