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99 results

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Page 1
Inhibition of p56(lck) tyrosine kinase by isothiazolones.
Trevillyan JM, Chiou XG, Ballaron SJ, Tang QM, Buko A, Sheets MP, Smith ML, Putman CB, Wiedeman P, Tu N, Madar D, Smith HT, Gubbins EJ, Warrior UP, Chen YW, Mollison KW, Faltynek CR, Djurić SW. Trevillyan JM, et al. Arch Biochem Biophys. 1999 Apr 1;364(1):19-29. doi: 10.1006/abbi.1999.1099. Arch Biochem Biophys. 1999. PMID: 10087161
Potent inhibition of NFAT activation and T cell cytokine production by novel low molecular weight pyrazole compounds.
Trevillyan JM, Chiou XG, Chen YW, Ballaron SJ, Sheets MP, Smith ML, Wiedeman PE, Warrior U, Wilkins J, Gubbins EJ, Gagne GD, Fagerland J, Carter GW, Luly JR, Mollison KW, Djuric SW. Trevillyan JM, et al. J Biol Chem. 2001 Dec 21;276(51):48118-26. doi: 10.1074/jbc.M107919200. Epub 2001 Oct 9. J Biol Chem. 2001. PMID: 11592964 Free article.
Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression.
Chen YW, Smith ML, Sheets M, Ballaron S, Trevillyan JM, Burke SE, Rosenberg T, Henry C, Wagner R, Bauch J, Marsh K, Fey TA, Hsieh G, Gauvin D, Mollison KW, Carter GW, Djuric SW. Chen YW, et al. Among authors: trevillyan jm. J Cardiovasc Pharmacol. 2007 Apr;49(4):228-35. doi: 10.1097/FJC.0b013e3180325b0a. J Cardiovasc Pharmacol. 2007. PMID: 17438408
3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator.
Djuric SW, BaMaung NY, Basha A, Liu H, Luly JR, Madar DJ, Sciotti RJ, Tu NP, Wagenaar FL, Wiedeman PE, Zhou X, Ballaron S, Bauch J, Chen YW, Chiou XG, Fey T, Gauvin D, Gubbins E, Hsieh GC, Marsh KC, Mollison KW, Pong M, Shaughnessy TK, Sheets MP, Smith M, Trevillyan JM, Warrior U, Wegner CD, Carter GW. Djuric SW, et al. Among authors: trevillyan jm. J Med Chem. 2000 Aug 10;43(16):2975-81. doi: 10.1021/jm990615a. J Med Chem. 2000. PMID: 10956206
Rapamycin analogs with reduced systemic exposure.
Wagner R, Mollison KW, Liu L, Henry CL, Rosenberg TA, Bamaung N, Tu N, Wiedeman PE, Or Y, Luly JR, Lane BC, Trevillyan J, Chen YW, Fey T, Hsieh G, Marsh K, Nuss M, Jacobson PB, Wilcox D, Carlson RP, Carter GW, Djuric SW. Wagner R, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5340-3. doi: 10.1016/j.bmcl.2005.06.106. Epub 2005 Sep 26. Bioorg Med Chem Lett. 2005. PMID: 16185865
PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.
Zinker BA, Rondinone CM, Trevillyan JM, Gum RJ, Clampit JE, Waring JF, Xie N, Wilcox D, Jacobson P, Frost L, Kroeger PE, Reilly RM, Koterski S, Opgenorth TJ, Ulrich RG, Crosby S, Butler M, Murray SF, McKay RA, Bhanot S, Monia BP, Jirousek MR. Zinker BA, et al. Among authors: trevillyan jm. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11357-62. doi: 10.1073/pnas.142298199. Epub 2002 Aug 8. Proc Natl Acad Sci U S A. 2002. PMID: 12169659 Free PMC article.
99 results