Van Breemen RB - Search Results

1

Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles.

Burdette JE, Chen SN, Lu ZZ, Xu H, White BE, Fabricant DS, Liu J, Fong HH, Farnsworth NR, Constantinou AI, Van Breemen RB, Pezzuto JM, Bolton JL. Burdette JE, et al. Among authors: van breemen rb. J Agric Food Chem. 2002 Nov 20;50(24):7022-8. doi: 10.1021/jf020725h. J Agric Food Chem. 2002. PMID: 12428954

2

Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.

Shen L, Pisha E, Huang Z, Pezzuto JM, Krol E, Alam Z, van Breemen RB, Bolton JL. Shen L, et al. Among authors: van breemen rb. Carcinogenesis. 1997 May;18(5):1093-101. doi: 10.1093/carcin/18.5.1093. Carcinogenesis. 1997. PMID: 9163701

3

The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells.

Bolton JL, Pisha E, Shen L, Krol ES, Iverson SL, Huang Z, van Breemen RB, Pezzuto JM. Bolton JL, et al. Among authors: van breemen rb. Chem Biol Interact. 1997 Sep 12;106(2):133-48. doi: 10.1016/s0009-2797(97)00066-5. Chem Biol Interact. 1997. PMID: 9366899

4

Metabolic screening using on-line ultrafiltration mass spectrometry.

van Breemen RB, Nikolic D, Bolton JL. van Breemen RB, et al. Drug Metab Dispos. 1998 Feb;26(2):85-90. Drug Metab Dispos. 1998. PMID: 9456292

5

Alkylation of 2'-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical.

Shen L, Qiu S, Chen Y, Zhang F, van Breemen RB, Nikolic D, Bolton JL. Shen L, et al. Among authors: van breemen rb. Chem Res Toxicol. 1998 Feb;11(2):94-101. doi: 10.1021/tx970181r. Chem Res Toxicol. 1998. PMID: 9511900

6

Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.

Chang M, Zhang F, Shen L, Pauss N, Alam I, van Breemen RB, Blond SY, Bolton JL. Chang M, et al. Among authors: van breemen rb. Chem Res Toxicol. 1998 Jul;11(7):758-65. doi: 10.1021/tx9702190. Chem Res Toxicol. 1998. PMID: 9671538

7

The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.

Chen Y, Shen L, Zhang F, Lau SS, van Breemen RB, Nikolic D, Bolton JL. Chen Y, et al. Among authors: van breemen rb. Chem Res Toxicol. 1998 Sep;11(9):1105-11. doi: 10.1021/tx980083l. Chem Res Toxicol. 1998. PMID: 9760286

8

The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.

Zhang F, Chen Y, Pisha E, Shen L, Xiong Y, van Breemen RB, Bolton JL. Zhang F, et al. Among authors: van breemen rb. Chem Res Toxicol. 1999 Feb;12(2):204-13. doi: 10.1021/tx980217v. Chem Res Toxicol. 1999. PMID: 10027800

9

Screening for xenobiotic electrophilic metabolites using pulsed ultrafiltration-mass spectrometry.

Nikolic D, Fan PW, Bolton JL, van Breemen RB. Nikolic D, et al. Among authors: van breemen rb. Comb Chem High Throughput Screen. 1999 Jun;2(3):165-75. Comb Chem High Throughput Screen. 1999. PMID: 10420970

10

Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity.

Chung HS, Chang LC, Lee SK, Shamon LA, van Breemen RB, Mehta RG, Farnsworth NR, Pezzuto JM, Kinghorn AD. Chung HS, et al. Among authors: van breemen rb. J Agric Food Chem. 1999 Jan;47(1):36-41. doi: 10.1021/jf980784o. J Agric Food Chem. 1999. PMID: 10563845

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