Hayter BR - Search Results

1

Enantioselective epoxidation of alkenes catalyzed by 2-fluoro-N-carbethoxytropinone and related tropinone derivatives.

Armstrong A, Ahmed G, Dominguez-Fernandez B, Hayter BR, Wailes JS. Armstrong A, et al. Among authors: hayter br. J Org Chem. 2002 Nov 29;67(24):8610-7. doi: 10.1021/jo026322y. J Org Chem. 2002. PMID: 12444645

2

Palladium-catalysed aminosulfonylation of aryl-, alkenyl- and heteroaryl halides: scope of the three-component synthesis of N-aminosulfonamides.

Emmett EJ, Richards-Taylor CS, Nguyen B, Garcia-Rubia A, Hayter BR, Willis MC. Emmett EJ, et al. Among authors: hayter br. Org Biomol Chem. 2012 May 28;10(20):4007-14. doi: 10.1039/c2ob07034k. Epub 2012 Mar 12. Org Biomol Chem. 2012. PMID: 22407213

3

Palladium-catalyzed three-component diaryl sulfone synthesis exploiting the sulfur dioxide surrogate DABSO.

Emmett EJ, Hayter BR, Willis MC. Emmett EJ, et al. Among authors: hayter br. Angew Chem Int Ed Engl. 2013 Nov 25;52(48):12679-83. doi: 10.1002/anie.201305369. Epub 2013 Oct 2. Angew Chem Int Ed Engl. 2013. PMID: 24115325 Free PMC article. No abstract available.

4

Palladium-catalyzed synthesis of ammonium sulfinates from aryl halides and a sulfur dioxide surrogate: a gas- and reductant-free process.

Emmett EJ, Hayter BR, Willis MC. Emmett EJ, et al. Among authors: hayter br. Angew Chem Int Ed Engl. 2014 Sep 15;53(38):10204-8. doi: 10.1002/anie.201404527. Epub 2014 Jul 27. Angew Chem Int Ed Engl. 2014. PMID: 25066222 Free PMC article.

5

Synthesis of cytidine ribonucleotides by stepwise assembly of the heterocycle on a sugar phosphate.

Ingar AA, Luke RW, Hayter BR, Sutherland JD. Ingar AA, et al. Among authors: hayter br. Chembiochem. 2003 Jun 6;4(6):504-7. doi: 10.1002/cbic.200300554. Chembiochem. 2003. PMID: 12794860

6

Modular Synthesis of Constrained Ethyl (cEt) Purine and Pyrimidine Nucleosides.

Blade H, Bradley D, Diorazio L, Evans T, Hayter BR, Howell GP. Blade H, et al. Among authors: hayter br. J Org Chem. 2015 May 15;80(10):5337-43. doi: 10.1021/acs.joc.5b00607. Epub 2015 Apr 28. J Org Chem. 2015. PMID: 25894018

7

Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.

De Savi C, Bradbury RH, Rabow AA, Norman RA, de Almeida C, Andrews DM, Ballard P, Buttar D, Callis RJ, Currie GS, Curwen JO, Davies CD, Donald CS, Feron LJ, Gingell H, Glossop SC, Hayter BR, Hussain S, Karoutchi G, Lamont SG, MacFaul P, Moss TA, Pearson SE, Tonge M, Walker GE, Weir HM, Wilson Z. De Savi C, et al. Among authors: hayter br. J Med Chem. 2015 Oct 22;58(20):8128-40. doi: 10.1021/acs.jmedchem.5b00984. Epub 2015 Oct 7. J Med Chem. 2015. PMID: 26407012

8

Novel thienopyrimidine and thiazolopyrimidine kinase inhibitors with activity against Tie-2 in vitro and in vivo.

Luke RW, Ballard P, Buttar D, Campbell L, Curwen J, Emery SC, Griffen AM, Hassall L, Hayter BR, Jones CD, McCoull W, Mellor M, Swain ML, Tucker JA. Luke RW, et al. Among authors: hayter br. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6670-4. doi: 10.1016/j.bmcl.2009.10.001. Epub 2009 Oct 13. Bioorg Med Chem Lett. 2009. PMID: 19854647

9

Discovery of imidazole vinyl pyrimidines as a novel class of kinase inhibitors which inhibit Tie-2 and are orally bioavailable.

Buttar D, Edge M, Emery SC, Fitzek M, Forder C, Griffen A, Hayter B, Hayward CF, Hopcroft PJ, Luke RW, Page K, Stawpert J, Wright A. Buttar D, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4723-6. doi: 10.1016/j.bmcl.2008.06.106. Epub 2008 Jul 23. Bioorg Med Chem Lett. 2008. PMID: 18676144

10

Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer.

Bradbury RH, Acton DG, Broadbent NL, Brooks AN, Carr GR, Hatter G, Hayter BR, Hill KJ, Howe NJ, Jones RD, Jude D, Lamont SG, Loddick SA, McFarland HL, Parveen Z, Rabow AA, Sharma-Singh G, Stratton NC, Thomason AG, Trueman D, Walker GE, Wells SL, Wilson J, Wood JM. Bradbury RH, et al. Among authors: hayter br. Bioorg Med Chem Lett. 2013 Apr 1;23(7):1945-8. doi: 10.1016/j.bmcl.2013.02.056. Epub 2013 Feb 21. Bioorg Med Chem Lett. 2013. PMID: 23466225

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