Huang M - Search Results

1

Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells.

Huang M, Dorsey JF, Epling-Burnette PK, Nimmanapalli R, Landowski TH, Mora LB, Niu G, Sinibaldi D, Bai F, Kraker A, Yu H, Moscinski L, Wei S, Djeu J, Dalton WS, Bhalla K, Loughran TP, Wu J, Jove R. Huang M, et al. Oncogene. 2002 Dec 12;21(57):8804-16. doi: 10.1038/sj.onc.1206028. Oncogene. 2002. PMID: 12483533

2

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.

Niu G, Wright KL, Huang M, Song L, Haura E, Turkson J, Zhang S, Wang T, Sinibaldi D, Coppola D, Heller R, Ellis LM, Karras J, Bromberg J, Pardoll D, Jove R, Yu H. Niu G, et al. Among authors: huang m. Oncogene. 2002 Mar 27;21(13):2000-8. doi: 10.1038/sj.onc.1205260. Oncogene. 2002. PMID: 11960372

3

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth.

Niu G, Bowman T, Huang M, Shivers S, Reintgen D, Daud A, Chang A, Kraker A, Jove R, Yu H. Niu G, et al. Among authors: huang m. Oncogene. 2002 Oct 10;21(46):7001-10. doi: 10.1038/sj.onc.1205859. Oncogene. 2002. PMID: 12370822

4

Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin.

Nimmanapalli R, O'Bryan E, Huang M, Bali P, Burnette PK, Loughran T, Tepperberg J, Jove R, Bhalla K. Nimmanapalli R, et al. Among authors: huang m. Cancer Res. 2002 Oct 15;62(20):5761-9. Cancer Res. 2002. PMID: 12384536

5

Inhibition of JAK kinase activity enhances Fas-mediated apoptosis but reduces cytotoxic activity of topoisomerase II inhibitors in U266 myeloma cells.

Oshiro MM, Landowski TH, Catlett-Falcone R, Hazlehurst LA, Huang M, Jove R, Dalton WS. Oshiro MM, et al. Among authors: huang m. Clin Cancer Res. 2001 Dec;7(12):4262-71. Clin Cancer Res. 2001. PMID: 11751528

6

Interleukin-3 protects Bcr-Abl-transformed hematopoietic progenitor cells from apoptosis induced by Bcr-Abl tyrosine kinase inhibitors.

Dorsey JF, Cunnick JM, Lanehart R, Huang M, Kraker AJ, Bhalla KN, Jove R, Wu J. Dorsey JF, et al. Among authors: huang m. Leukemia. 2002 Sep;16(9):1589-95. doi: 10.1038/sj.leu.2402678. Leukemia. 2002. PMID: 12200668

7

Flavopiridol down-regulates antiapoptotic proteins and sensitizes human breast cancer cells to epothilone B-induced apoptosis.

Wittmann S, Bali P, Donapaty S, Nimmanapalli R, Guo F, Yamaguchi H, Huang M, Jove R, Wang HG, Bhalla K. Wittmann S, et al. Among authors: huang m. Cancer Res. 2003 Jan 1;63(1):93-9. Cancer Res. 2003. PMID: 12517783

8

Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.

Nefedova Y, Huang M, Kusmartsev S, Bhattacharya R, Cheng P, Salup R, Jove R, Gabrilovich D. Nefedova Y, et al. Among authors: huang m. J Immunol. 2004 Jan 1;172(1):464-74. doi: 10.4049/jimmunol.172.1.464. J Immunol. 2004. PMID: 14688356

9

Role of Stat3 in regulating p53 expression and function.

Niu G, Wright KL, Ma Y, Wright GM, Huang M, Irby R, Briggs J, Karras J, Cress WD, Pardoll D, Jove R, Chen J, Yu H. Niu G, et al. Among authors: huang m. Mol Cell Biol. 2005 Sep;25(17):7432-40. doi: 10.1128/MCB.25.17.7432-7440.2005. Mol Cell Biol. 2005. PMID: 16107692 Free PMC article.

10

Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest.

Niu G, Shain KH, Huang M, Ravi R, Bedi A, Dalton WS, Jove R, Yu H. Niu G, et al. Among authors: huang m. Cancer Res. 2001 Apr 15;61(8):3276-80. Cancer Res. 2001. PMID: 11309279

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