Lépine S - Search Results

1

Involvement of sphingosine in dexamethasone-induced thymocyte apoptosis.

Lépine S, Lakatos B, Maziere P, Courageot MP, Sulpice JC, Giraud F. Lépine S, et al. Ann N Y Acad Sci. 2002 Nov;973:190-3. doi: 10.1111/j.1749-6632.2002.tb04631.x. Ann N Y Acad Sci. 2002. PMID: 12485859

2

ATP-induced apoptosis of thymocytes is mediated by activation of P2 X 7 receptor and involves de novo ceramide synthesis and mitochondria.

Lépine S, Le Stunff H, Lakatos B, Sulpice JC, Giraud F. Lépine S, et al. Biochim Biophys Acta. 2006 Jan;1761(1):73-82. doi: 10.1016/j.bbalip.2005.10.001. Epub 2005 Oct 24. Biochim Biophys Acta. 2006. PMID: 16325464

3

Extracellular ATP induces phosphatidylserine externalization earlier than nuclear apoptotic events in thymocytes.

Courageot MP, Lepine S, Giraud F, Sulpice JC. Courageot MP, et al. Among authors: lepine s. Ann N Y Acad Sci. 2002 Nov;973:186-9. doi: 10.1111/j.1749-6632.2002.tb04630.x. Ann N Y Acad Sci. 2002. PMID: 12485858

4

Involvement of sodium in early phosphatidylserine exposure and phospholipid scrambling induced by P2X7 purinoceptor activation in thymocytes.

Courageot MP, Lépine S, Hours M, Giraud F, Sulpice JC. Courageot MP, et al. Among authors: lepine s. J Biol Chem. 2004 May 21;279(21):21815-23. doi: 10.1074/jbc.M401426200. Epub 2004 Mar 2. J Biol Chem. 2004. PMID: 14996828 Free article.

5

Sphingosine contributes to glucocorticoid-induced apoptosis of thymocytes independently of the mitochondrial pathway.

Lépine S, Lakatos B, Courageot MP, Le Stunff H, Sulpice JC, Giraud F. Lépine S, et al. J Immunol. 2004 Sep 15;173(6):3783-90. doi: 10.4049/jimmunol.173.6.3783. J Immunol. 2004. PMID: 15356125

6

Signaling pathways involved in glucocorticoid-induced apoptosis of thymocytes.

Lépine S, Sulpice JC, Giraud F. Lépine S, et al. Crit Rev Immunol. 2005;25(4):263-88. doi: 10.1615/critrevimmunol.v25.i4.20. Crit Rev Immunol. 2005. PMID: 16167881 Review.

7

Autophagy induced by deficiency of sphingosine-1-phosphate phosphohydrolase 1 is switched to apoptosis by calpain-mediated autophagy-related gene 5 (Atg5) cleavage.

Lépine S, Allegood JC, Edmonds Y, Milstien S, Spiegel S. Lépine S, et al. J Biol Chem. 2011 Dec 30;286(52):44380-90. doi: 10.1074/jbc.M111.257519. Epub 2011 Nov 3. J Biol Chem. 2011. PMID: 22052905 Free PMC article.

Depletion of S1P phosphohydrolase-1 (SPP1), which degrades intracellular S1P, induces the unfolded protein response and endoplasmic reticulum stress-induced autophagy (Lepine, S., Allegood, J. C., Park, M., Dent, P., Milstien, S., and Spiegel, S. (2011 …

Depletion of S1P phosphohydrolase-1 (SPP1), which degrades intracellular S1P, induces the unfolded protein response and endoplasmic reticulu …

8

Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide.

Giussani P, Maceyka M, Le Stunff H, Mikami A, Lépine S, Wang E, Kelly S, Merrill AH Jr, Milstien S, Spiegel S. Giussani P, et al. Among authors: lepine s. Mol Cell Biol. 2006 Jul;26(13):5055-69. doi: 10.1128/MCB.02107-05. Mol Cell Biol. 2006. PMID: 16782891 Free PMC article.

9

Recycling of sphingosine is regulated by the concerted actions of sphingosine-1-phosphate phosphohydrolase 1 and sphingosine kinase 2.

Le Stunff H, Giussani P, Maceyka M, Lépine S, Milstien S, Spiegel S. Le Stunff H, et al. Among authors: lepine s. J Biol Chem. 2007 Nov 23;282(47):34372-80. doi: 10.1074/jbc.M703329200. Epub 2007 Sep 25. J Biol Chem. 2007. PMID: 17895250 Free article.

10

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy.

Lépine S, Allegood JC, Park M, Dent P, Milstien S, Spiegel S. Lépine S, et al. Cell Death Differ. 2011 Feb;18(2):350-61. doi: 10.1038/cdd.2010.104. Epub 2010 Aug 27. Cell Death Differ. 2011. PMID: 20798685 Free PMC article.

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