Pawson T - Search Results

1

Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity.

Tong J, Elowe S, Nash P, Pawson T. Tong J, et al. Among authors: pawson t. J Biol Chem. 2003 Feb 21;278(8):6111-9. doi: 10.1074/jbc.M208972200. Epub 2002 Dec 16. J Biol Chem. 2003. PMID: 12486127 Free article.

2

Netrin stimulates tyrosine phosphorylation of the UNC-5 family of netrin receptors and induces Shp2 binding to the RCM cytodomain.

Tong J, Killeen M, Steven R, Binns KL, Culotti J, Pawson T. Tong J, et al. Among authors: pawson t. J Biol Chem. 2001 Nov 2;276(44):40917-25. doi: 10.1074/jbc.M103872200. Epub 2001 Aug 30. J Biol Chem. 2001. PMID: 11533026 Free article.

3

Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction.

Elowe S, Holland SJ, Kulkarni S, Pawson T. Elowe S, et al. Among authors: pawson t. Mol Cell Biol. 2001 Nov;21(21):7429-41. doi: 10.1128/MCB.21.21.7429-7441.2001. Mol Cell Biol. 2001. PMID: 11585923 Free PMC article.

4

The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network.

Bladt F, Aippersbach E, Gelkop S, Strasser GA, Nash P, Tafuri A, Gertler FB, Pawson T. Bladt F, et al. Among authors: pawson t. Mol Cell Biol. 2003 Jul;23(13):4586-97. doi: 10.1128/MCB.23.13.4586-4597.2003. Mol Cell Biol. 2003. PMID: 12808099 Free PMC article.

5

The human and mouse complement of SH2 domain proteins-establishing the boundaries of phosphotyrosine signaling.

Liu BA, Jablonowski K, Raina M, Arcé M, Pawson T, Nash PD. Liu BA, et al. Among authors: pawson t. Mol Cell. 2006 Jun 23;22(6):851-868. doi: 10.1016/j.molcel.2006.06.001. Mol Cell. 2006. PMID: 16793553 Free article.

6

Interaction domains: from simple binding events to complex cellular behavior.

Pawson T, Raina M, Nash P. Pawson T, et al. FEBS Lett. 2002 Feb 20;513(1):2-10. doi: 10.1016/s0014-5793(01)03292-6. FEBS Lett. 2002. PMID: 11911873 Free article. Review.

7

A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling.

Berry DM, Nash P, Liu SK, Pawson T, McGlade CJ. Berry DM, et al. Among authors: pawson t. Curr Biol. 2002 Aug 6;12(15):1336-41. doi: 10.1016/s0960-9822(02)01038-2. Curr Biol. 2002. PMID: 12176364 Free article.

8

Assembly of cell regulatory systems through protein interaction domains.

Pawson T, Nash P. Pawson T, et al. Science. 2003 Apr 18;300(5618):445-52. doi: 10.1126/science.1083653. Science. 2003. PMID: 12702867 Review.

9

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.

Wybenga-Groot LE, Baskin B, Ong SH, Tong J, Pawson T, Sicheri F. Wybenga-Groot LE, et al. Among authors: pawson t. Cell. 2001 Sep 21;106(6):745-57. doi: 10.1016/s0092-8674(01)00496-2. Cell. 2001. PMID: 11572780 Free article.

10

SH2 domains, interaction modules and cellular wiring.

Pawson T, Gish GD, Nash P. Pawson T, et al. Trends Cell Biol. 2001 Dec;11(12):504-11. doi: 10.1016/s0962-8924(01)02154-7. Trends Cell Biol. 2001. PMID: 11719057 Review.

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