Kohl NE - Search Results

1

Farnesyl:protein transferase inhibitors as potential agents for the management of human prostate cancer.

Sepp-Lorenzino L, Tjaden G, Moasser MM, Timaul N, Ma Z, Kohl NE, Gibbs JB, Oliff A, Rosen N, Scher HI. Sepp-Lorenzino L, et al. Among authors: kohl ne. Prostate Cancer Prostatic Dis. 2001;4(1):33-43. doi: 10.1038/sj.pcan.4500491. Prostate Cancer Prostatic Dis. 2001. PMID: 12497061

2

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines.

Sepp-Lorenzino L, Ma Z, Rands E, Kohl NE, Gibbs JB, Oliff A, Rosen N. Sepp-Lorenzino L, et al. Among authors: kohl ne. Cancer Res. 1995 Nov 15;55(22):5302-9. Cancer Res. 1995. PMID: 7585592

3

cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I.

Zhang FL, Diehl RE, Kohl NE, Gibbs JB, Giros B, Casey PJ, Omer CA. Zhang FL, et al. Among authors: kohl ne. J Biol Chem. 1994 Feb 4;269(5):3175-80. J Biol Chem. 1994. PMID: 8106351 Free article.

4

Pseudopeptide inhibitors of Ras farnesyl-protein transferase.

Graham SL, deSolms SJ, Giuliani EA, Kohl NE, Mosser SD, Oliff AI, Pompliano DL, Rands E, Breslin MJ, Deana AA, et al. Graham SL, et al. Among authors: kohl ne. J Med Chem. 1994 Mar 18;37(6):725-32. doi: 10.1021/jm00032a004. J Med Chem. 1994. PMID: 8145221

5

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic.

Gibbs JB, Oliff A, Kohl NE. Gibbs JB, et al. Among authors: kohl ne. Cell. 1994 Apr 22;77(2):175-8. doi: 10.1016/0092-8674(94)90308-5. Cell. 1994. PMID: 8168127 Review. No abstract available.

6

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton.

Prendergast GC, Davide JP, deSolms SJ, Giuliani EA, Graham SL, Gibbs JB, Oliff A, Kohl NE. Prendergast GC, et al. Among authors: kohl ne. Mol Cell Biol. 1994 Jun;14(6):4193-202. doi: 10.1128/mcb.14.6.4193-4202.1994. Mol Cell Biol. 1994. PMID: 8196657 Free PMC article.

7

Negative growth selection against rodent fibroblasts targeted for genetic inhibition of farnesyl transferase.

Prendergast GC, Davide JP, Kral A, Diehl R, Gibbs JB, Omer CA, Kohl NE. Prendergast GC, et al. Among authors: kohl ne. Cell Growth Differ. 1993 Sep;4(9):707-13. Cell Growth Differ. 1993. PMID: 8241019

8

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor.

Kohl NE, Mosser SD, deSolms SJ, Giuliani EA, Pompliano DL, Graham SL, Smith RL, Scolnick EM, Oliff A, Gibbs JB. Kohl NE, et al. Science. 1993 Jun 25;260(5116):1934-7. doi: 10.1126/science.8316833. Science. 1993. PMID: 8316833

9

Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.

Gibbs JB, Pompliano DL, Mosser SD, Rands E, Lingham RB, Singh SB, Scolnick EM, Kohl NE, Oliff A. Gibbs JB, et al. Among authors: kohl ne. J Biol Chem. 1993 Apr 15;268(11):7617-20. J Biol Chem. 1993. PMID: 8463291 Free article.

10

Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases.

Omer CA, Kral AM, Diehl RE, Prendergast GC, Powers S, Allen CM, Gibbs JB, Kohl NE. Omer CA, et al. Among authors: kohl ne. Biochemistry. 1993 May 18;32(19):5167-76. doi: 10.1021/bi00070a028. Biochemistry. 1993. PMID: 8494894

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