Qiu Q - Search Results

1

The combi-targeting concept: a novel 3,3-disubstituted nitrosourea with EGFR tyrosine kinase inhibitory properties.

Qiu Q, Dudouit F, Matheson SL, Brahimi F, Banerjee R, McNamee JP, Jean-Claude BJ. Qiu Q, et al. Cancer Chemother Pharmacol. 2003 Jan;51(1):1-10. doi: 10.1007/s00280-002-0524-5. Epub 2002 Nov 1. Cancer Chemother Pharmacol. 2003. PMID: 12497200

2

Sustained antiproliferative mechanisms by RB24, a targeted precursor of multiple inhibitors of epidermal growth factor receptor and a DNA alkylating agent in the A431 epidermal carcinoma of the vulva cell line.

Banerjee R, Rachid Z, Qiu Q, McNamee JP, Tari AM, Jean-Claude BJ. Banerjee R, et al. Among authors: qiu q. Br J Cancer. 2004 Sep 13;91(6):1066-73. doi: 10.1038/sj.bjc.6602098. Br J Cancer. 2004. PMID: 15365562 Free PMC article.

3

Inhibition of cell signaling by the combi-nitrosourea FD137 in the androgen independent DU145 prostate cancer cell line.

Qiu Q, Dudouit F, Banerjee R, McNamee JP, Jean-Claude BJ. Qiu Q, et al. Prostate. 2004 Apr 1;59(1):13-21. doi: 10.1002/pros.10353. Prostate. 2004. PMID: 14991862

4

Multiple mechanisms of action of ZR2002 in human breast cancer cells: a novel combi-molecule designed to block signaling mediated by the ERB family of oncogenes and to damage genomic DNA.

Brahimi F, Rachid Z, Qiu Q, McNamee JP, Li YJ, Tari AM, Jean-Claude BJ. Brahimi F, et al. Among authors: qiu q. Int J Cancer. 2004 Nov 10;112(3):484-91. doi: 10.1002/ijc.20383. Int J Cancer. 2004. PMID: 15382076

5

[Combi-molecules: a global approach towards better chemoselectivity and chemosensitivity].

Matheson S, Qiu Q, Brahimi F, Dudouit F, Banerjee R, Rachid Z, Jean-Claude BJ. Matheson S, et al. Among authors: qiu q. Bull Cancer. 2004 Dec;91(12):911-5. Bull Cancer. 2004. PMID: 15634632 Free article. French.

6

The combi-targeting concept: evidence for the formation of a novel inhibitor in vivo.

Merayo N, Rachid Z, Qiu Q, Brahimi F, Jean-Claude BJ. Merayo N, et al. Among authors: qiu q. Anticancer Drugs. 2006 Feb;17(2):165-71. doi: 10.1097/00001813-200602000-00007. Anticancer Drugs. 2006. PMID: 16428934

7

Type II combi-molecules: design and binary targeting properties of the novel triazolinium-containing molecules JDD36 and JDE05.

Qiu Q, Domarkas J, Banerjee R, Katsoulas A, McNamee JP, Jean-Claude BJ. Qiu Q, et al. Anticancer Drugs. 2007 Feb;18(2):171-7. doi: 10.1097/CAD.0b013e3280115fe8. Anticancer Drugs. 2007. PMID: 17159603

8

The combi-targeting concept: in vitro and in vivo fragmentation of a stable combi-nitrosourea engineered to interact with the epidermal growth factor receptor while remaining DNA reactive.

Qiu Q, Domarkas J, Banerjee R, Merayo N, Brahimi F, McNamee JP, Gibbs BF, Jean-Claude BJ. Qiu Q, et al. Clin Cancer Res. 2007 Jan 1;13(1):331-40. doi: 10.1158/1078-0432.CCR-06-0812. Clin Cancer Res. 2007. PMID: 17200372

9

Novel nitrogen mustard-armed combi-molecules for the selective targeting of epidermal growth factor receptor overexperessing solid tumors: discovery of an unusual structure-activity relationship.

Rachid Z, Brahimi F, Qiu Q, Williams C, Hartley JM, Hartley JA, Jean-Claude BJ. Rachid Z, et al. Among authors: qiu q. J Med Chem. 2007 May 31;50(11):2605-8. doi: 10.1021/jm070144p. Epub 2007 May 2. J Med Chem. 2007. PMID: 17472358

10

Characterization of the potency of epidermal growth factor (EGFR)-DNA targeting combi-molecules containing a hydrolabile carbamate at the 3-position of the triazene chain.

MacPhee M, Rachid Z, Todorova M, Qiu Q, Belinsky G, Jean-Claude BJ. MacPhee M, et al. Among authors: qiu q. Invest New Drugs. 2011 Oct;29(5):833-45. doi: 10.1007/s10637-010-9431-5. Epub 2010 Apr 29. Invest New Drugs. 2011. PMID: 20428924

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