Leclercq G - Search Results

1

Synthesis, characterization and biological evaluation of 7 alpha-perfluoroalkylestradiol derivatives.

Blazejewski JC, Wilmshurst MP, Popkin MD, Wakselman C, Laurent G, Nonclercq D, Cleeren A, Ma Y, Seo HS, Leclercq G. Blazejewski JC, et al. Among authors: leclercq g. Bioorg Med Chem. 2003 Feb 6;11(3):335-45. doi: 10.1016/s0968-0896(02)00457-1. Bioorg Med Chem. 2003. PMID: 12517429

2

Hexestrol-linked cytotoxic agents: synthesis and binding affinity for estrogen receptors.

Köhle H, Krohn K, Leclercq G. Köhle H, et al. Among authors: leclercq g. J Med Chem. 1989 Jul;32(7):1538-47. doi: 10.1021/jm00127a023. J Med Chem. 1989. PMID: 2544725

3

Derivatives of tamoxifen. Dependence of antiestrogenicity on the 4-substituent.

McCague R, Leclercq G, Legros N, Goodman J, Blackburn GM, Jarman M, Foster AB. McCague R, et al. Among authors: leclercq g. J Med Chem. 1989 Dec;32(12):2527-33. doi: 10.1021/jm00132a006. J Med Chem. 1989. PMID: 2585441

4

Hydroxy derivatives of tamoxifen.

Foster AB, Jarman M, Leung OT, McCague R, Leclercq G, Devleeschouwer N. Foster AB, et al. Among authors: leclercq g. J Med Chem. 1985 Oct;28(10):1491-7. doi: 10.1021/jm00148a020. J Med Chem. 1985. PMID: 4045924

5

Estrogenic and antiestrogenic regulation of the half-life of covalently labeled estrogen receptor in MCF-7 breast cancer cells.

Borrás M, Laios I, el Khissiin A, Seo HS, Lempereur F, Legros N, Leclercq G. Borrás M, et al. Among authors: leclercq g. J Steroid Biochem Mol Biol. 1996 Feb;57(3-4):203-13. doi: 10.1016/0960-0760(95)00272-3. J Steroid Biochem Mol Biol. 1996. PMID: 8645630

6

Protein synthesis is not implicated in the ligand-dependent activation of the estrogen receptor in MCF-7 cells.

El Khissiin A, Cleeren A, Borràs M, Leclercq G. El Khissiin A, et al. Among authors: leclercq g. J Steroid Biochem Mol Biol. 1997 Jul;62(4):269-76. doi: 10.1016/s0960-0760(97)00047-2. J Steroid Biochem Mol Biol. 1997. PMID: 9408080

7

Estrogenic and anti-estrogenic regulation of estrogen receptor in MCF-7 breast-cancer cells: comparison of immunocytochemical data with biochemical measurements.

Seo HS, Larsimont D, Querton G, El Khissiin A, Laios I, Legros N, Leclercq G. Seo HS, et al. Among authors: leclercq g. Int J Cancer. 1998 Dec 9;78(6):760-5. doi: 10.1002/(sici)1097-0215(19981209)78:6<760::aid-ijc14>3.0.co;2-u. Int J Cancer. 1998. PMID: 9833770

8

Regulation of estrogen receptor levels by ligand-induced release of compound(s) in MCF-7 cells.

Seo HS, Larsimont D, Ma Y, Laios I, Leclercq G. Seo HS, et al. Among authors: leclercq g. Mol Cell Endocrinol. 2000 Jun;164(1-2):19-29. doi: 10.1016/s0303-7207(00)00244-6. Mol Cell Endocrinol. 2000. PMID: 11026554

9

Evidence of an estrogen receptor form devoid of estrogen binding ability in MCF-7 cells.

El Khissiin A, Journé F, Laïos I, Seo HS, Leclercq G. El Khissiin A, et al. Among authors: leclercq g. Steroids. 2000 Dec;65(12):903-13. doi: 10.1016/s0039-128x(00)00206-3. Steroids. 2000. PMID: 11077089

10

Diphenyl quinolines and isoquinolines: synthesis and primary biological evaluation.

Croisy-Delcey M, Croisy A, Carrez D, Huel C, Chiaroni A, Ducrot P, Bisagni E, Jin L, Leclercq G. Croisy-Delcey M, et al. Among authors: leclercq g. Bioorg Med Chem. 2000 Nov;8(11):2629-41. doi: 10.1016/s0968-0896(00)00194-2. Bioorg Med Chem. 2000. PMID: 11092548

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