Gonsiorek W - Search Results

1

The study of CXCR3 and CCR7 pharmacology using [35S]GTPgammaS exchange assays in cell membranes and permeabilized peripheral blood lymphocytes.

Gonsiorek W, Zavodny P, Hipkin RW. Gonsiorek W, et al. J Immunol Methods. 2003 Feb;273(1-2):15-27. doi: 10.1016/s0022-1759(02)00415-5. J Immunol Methods. 2003. PMID: 12535794

2

Human interferon-inducible 10-kDa protein and human interferon-inducible T cell alpha chemoattractant are allotopic ligands for human CXCR3: differential binding to receptor states.

Cox MA, Jenh CH, Gonsiorek W, Fine J, Narula SK, Zavodny PJ, Hipkin RW. Cox MA, et al. Among authors: gonsiorek w. Mol Pharmacol. 2001 Apr;59(4):707-15. doi: 10.1124/mol.59.4.707. Mol Pharmacol. 2001. PMID: 11259614

3

Pharmacological characterization of the chemokine receptor, hCCR1 in a stable transfectant and differentiated HL-60 cells: antagonism of hCCR1 activation by MIP-1beta.

Chou CC, Fine JS, Pugliese-Sivo C, Gonsiorek W, Davies L, Deno G, Petro M, Schwarz M, Zavodny PJ, Hipkin RW. Chou CC, et al. Among authors: gonsiorek w. Br J Pharmacol. 2002 Nov;137(5):663-75. doi: 10.1038/sj.bjp.0704907. Br J Pharmacol. 2002. PMID: 12381680 Free PMC article.

4

Cloning and pharmacological characterization of CXCR1 and CXCR2 from Macaca fascicularis.

Hipkin RW, Deno G, Fine J, Sun Y, Wilburn B, Fan X, Gonsiorek W, Wiekowski MT. Hipkin RW, et al. Among authors: gonsiorek w. J Pharmacol Exp Ther. 2004 Jul;310(1):291-300. doi: 10.1124/jpet.103.063131. Epub 2004 Mar 17. J Pharmacol Exp Ther. 2004. PMID: 15028780 Free article.

5

Pharmacological characterization of human S1P4 using a novel radioligand, [4,5-3H]-dihydrosphingosine-1-phosphate.

Fossetta J, Deno G, Gonsiorek W, Fan X, Lavey B, Das P, Lunn C, Zavodny PJ, Lundell D, Hipkin RW. Fossetta J, et al. Among authors: gonsiorek w. Br J Pharmacol. 2004 Jul;142(5):851-60. doi: 10.1038/sj.bjp.0705856. Epub 2004 Jun 14. Br J Pharmacol. 2004. PMID: 15197107 Free PMC article.

6

Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies.

Lavey BJ, Kozlowski JA, Hipkin RW, Gonsiorek W, Lundell DJ, Piwinski JJ, Narula S, Lunn CA. Lavey BJ, et al. Among authors: gonsiorek w. Bioorg Med Chem Lett. 2005 Feb 1;15(3):783-6. doi: 10.1016/j.bmcl.2004.11.007. Bioorg Med Chem Lett. 2005. PMID: 15664857

7

A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo.

Lunn CA, Fine JS, Rojas-Triana A, Jackson JV, Fan X, Kung TT, Gonsiorek W, Schwarz MA, Lavey B, Kozlowski JA, Narula SK, Lundell DJ, Hipkin RW, Bober LA. Lunn CA, et al. Among authors: gonsiorek w. J Pharmacol Exp Ther. 2006 Feb;316(2):780-8. doi: 10.1124/jpet.105.093500. Epub 2005 Oct 28. J Pharmacol Exp Ther. 2006. PMID: 16258021

8

Discovery and characterization of vicriviroc (SCH 417690), a CCR5 antagonist with potent activity against human immunodeficiency virus type 1.

Strizki JM, Tremblay C, Xu S, Wojcik L, Wagner N, Gonsiorek W, Hipkin RW, Chou CC, Pugliese-Sivo C, Xiao Y, Tagat JR, Cox K, Priestley T, Sorota S, Huang W, Hirsch M, Reyes GR, Baroudy BM. Strizki JM, et al. Among authors: gonsiorek w. Antimicrob Agents Chemother. 2005 Dec;49(12):4911-9. doi: 10.1128/AAC.49.12.4911-4919.2005. Antimicrob Agents Chemother. 2005. PMID: 16304152 Free PMC article.

9

Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S]Sch225336.

Gonsiorek W, Hesk D, Chen SC, Kinsley D, Fine JS, Jackson JV, Bober LA, Deno G, Bian H, Fossetta J, Lunn CA, Kozlowski JA, Lavey B, Piwinski J, Narula SK, Lundell DJ, Hipkin RW. Gonsiorek W, et al. J Biol Chem. 2006 Sep 22;281(38):28143-51. doi: 10.1074/jbc.M602364200. Epub 2006 Jun 5. J Biol Chem. 2006. PMID: 16754676 Free article.

10

Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8.

Fan X, Patera AC, Pong-Kennedy A, Deno G, Gonsiorek W, Manfra DJ, Vassileva G, Zeng M, Jackson C, Sullivan L, Sharif-Rodriguez W, Opdenakker G, Van Damme J, Hedrick JA, Lundell D, Lira SA, Hipkin RW. Fan X, et al. Among authors: gonsiorek w. J Biol Chem. 2007 Apr 20;282(16):11658-66. doi: 10.1074/jbc.M607705200. Epub 2006 Dec 29. J Biol Chem. 2007. PMID: 17197447 Free article.

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