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Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins.
Cordle SR, Henderson E, Masuoka H, Weil PA, Stein R. Cordle SR, et al. Among authors: stein r. Mol Cell Biol. 1991 Mar;11(3):1734-8. doi: 10.1128/mcb.11.3.1734-1738.1991. Mol Cell Biol. 1991. PMID: 1996119 Free PMC article.
Antibody to the E12/E47 B-HLH proteins attenuated the formation, in vitro, of a previously described (J. Whelan, S. R. Cordle, E. Henderson, P. A. Weil, and R. Stein, Mol. Cell. Biol. 10:1564-1572, 1990) beta-cell-specific activator factor(s)-ICE DNA complex. …
Antibody to the E12/E47 B-HLH proteins attenuated the formation, in vitro, of a previously described (J. Whelan, S. R. Cordle, E. Hen …
Identification of a pancreatic beta-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence.
Whelan J, Cordle SR, Henderson E, Weil PA, Stein R. Whelan J, et al. Among authors: stein r. Mol Cell Biol. 1990 Apr;10(4):1564-72. doi: 10.1128/mcb.10.4.1564-1572.1990. Mol Cell Biol. 1990. PMID: 2181278 Free PMC article.
c-jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene products.
Robinson GL, Henderson E, Massari ME, Murre C, Stein R. Robinson GL, et al. Among authors: stein r. Mol Cell Biol. 1995 Mar;15(3):1398-404. doi: 10.1128/MCB.15.3.1398. Mol Cell Biol. 1995. PMID: 7862133 Free PMC article.
Previous experiments showed that ICE activation in beta cells was repressed in vivo by the c-jun proto-oncogene (E. Henderson and R. Stein, Mol. Cell. Biol. 14:655-662, 1994). Here we focus on the mechanism by which c-Jun inhibits ICE-mediated activation. c-Jun was …
Previous experiments showed that ICE activation in beta cells was repressed in vivo by the c-jun proto-oncogene (E. Henderson and R. …
3,111 results