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Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease.
Hudry E, Van Dam D, Kulik W, De Deyn PP, Stet FS, Ahouansou O, Benraiss A, Delacourte A, Bougnères P, Aubourg P, Cartier N. Hudry E, et al. Among authors: de deyn pp. Mol Ther. 2010 Jan;18(1):44-53. doi: 10.1038/mt.2009.175. Epub 2009 Aug 4. Mol Ther. 2010. PMID: 19654569 Free PMC article.
No correlation between time-linked plasma and CSF Abeta levels.
Le Bastard N, Aerts L, Leurs J, Blomme W, De Deyn PP, Engelborghs S. Le Bastard N, et al. Among authors: de deyn pp. Neurochem Int. 2009 Dec;55(8):820-5. doi: 10.1016/j.neuint.2009.08.006. Epub 2009 Aug 18. Neurochem Int. 2009. PMID: 19695299
Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis.
de Bock L, Somers K, Fraussen J, Hendriks JJ, van Horssen J, Rouwette M, Hellings N, Villar LM, Alvarez-Cermeño JC, Espiño M, Hupperts R, Jongen P, Damoiseaux J, Verbeek MM, De Deyn PP, D'hooghe M, Van Wijmeersch B, Stinissen P, Somers V. de Bock L, et al. Among authors: de deyn pp. J Immunol. 2014 Sep 1;193(5):2147-56. doi: 10.4049/jimmunol.1401166. Epub 2014 Aug 1. J Immunol. 2014. PMID: 25086173 Clinical Trial.
801 results