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Page 1
beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi.
Baillie GS, Sood A, McPhee I, Gall I, Perry SJ, Lefkowitz RJ, Houslay MD. Baillie GS, et al. Among authors: gall i. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):940-5. doi: 10.1073/pnas.262787199. Epub 2003 Jan 27. Proc Natl Acad Sci U S A. 2003. Retraction in: Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2205198119. doi: 10.1073/pnas.2205198119 PMID: 12552097 Free PMC article. Retracted.
PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).
Cheung YF, Kan Z, Garrett-Engele P, Gall I, Murdoch H, Baillie GS, Camargo LM, Johnson JM, Houslay MD, Castle JC. Cheung YF, et al. Among authors: gall i. J Pharmacol Exp Ther. 2007 Aug;322(2):600-9. doi: 10.1124/jpet.107.122218. Epub 2007 May 22. J Pharmacol Exp Ther. 2007. PMID: 17519386 Free article.
TAPAS-1, a novel microdomain within the unique N-terminal region of the PDE4A1 cAMP-specific phosphodiesterase that allows rapid, Ca2+-triggered membrane association with selectivity for interaction with phosphatidic acid.
Baillie GS, Huston E, Scotland G, Hodgkin M, Gall I, Peden AH, MacKenzie C, Houslay ES, Currie R, Pettitt TR, Walmsley AR, Wakelam MJ, Warwicker J, Houslay MD. Baillie GS, et al. Among authors: gall i. J Biol Chem. 2002 Aug 2;277(31):28298-309. doi: 10.1074/jbc.M108353200. Epub 2002 May 6. J Biol Chem. 2002. PMID: 11994273 Free article.
In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region.
McCahill A, McSorley T, Huston E, Hill EV, Lynch MJ, Gall I, Keryer G, Lygren B, Tasken K, van Heeke G, Houslay MD. McCahill A, et al. Among authors: gall i. Cell Signal. 2005 Sep;17(9):1158-73. doi: 10.1016/j.cellsig.2005.04.003. Cell Signal. 2005. PMID: 15905070
Compartmentalization of cAMP-dependent signaling by phosphodiesterase-4D is involved in the regulation of vasopressin-mediated water reabsorption in renal principal cells.
Stefan E, Wiesner B, Baillie GS, Mollajew R, Henn V, Lorenz D, Furkert J, Santamaria K, Nedvetsky P, Hundsrucker C, Beyermann M, Krause E, Pohl P, Gall I, MacIntyre AN, Bachmann S, Houslay MD, Rosenthal W, Klussmann E. Stefan E, et al. Among authors: gall i. J Am Soc Nephrol. 2007 Jan;18(1):199-212. doi: 10.1681/ASN.2006020132. Epub 2006 Nov 29. J Am Soc Nephrol. 2007. PMID: 17135396
63 results