Lefkowitz RJ - Search Results

1

beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi.

Baillie GS, Sood A, McPhee I, Gall I, Perry SJ, Lefkowitz RJ, Houslay MD. Baillie GS, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):940-5. doi: 10.1073/pnas.262787199. Epub 2003 Jan 27. Proc Natl Acad Sci U S A. 2003. Retraction in: Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2205198119. doi: 10.1073/pnas.2205198119 PMID: 12552097 Free PMC article. Retracted.

2

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase.

Roth NS, Campbell PT, Caron MG, Lefkowitz RJ, Lohse MJ. Roth NS, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6201-4. doi: 10.1073/pnas.88.14.6201. Proc Natl Acad Sci U S A. 1991. PMID: 1648731 Free PMC article.

3

The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase.

Lorenz W, Inglese J, Palczewski K, Onorato JJ, Caron MG, Lefkowitz RJ. Lorenz W, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8715-9. doi: 10.1073/pnas.88.19.8715. Proc Natl Acad Sci U S A. 1991. PMID: 1656454 Free PMC article.

4

Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor.

Valiquette M, Bonin H, Hnatowich M, Caron MG, Lefkowitz RJ, Bouvier M. Valiquette M, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1990 Jul;87(13):5089-93. doi: 10.1073/pnas.87.13.5089. Proc Natl Acad Sci U S A. 1990. PMID: 2164220 Free PMC article.

5

Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein).

Benovic JL, Kühn H, Weyand I, Codina J, Caron MG, Lefkowitz RJ. Benovic JL, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1987 Dec;84(24):8879-82. doi: 10.1073/pnas.84.24.8879. Proc Natl Acad Sci U S A. 1987. PMID: 2827157 Free PMC article.

6

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.

Koch WJ, Hawes BE, Allen LF, Lefkowitz RJ. Koch WJ, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12706-10. doi: 10.1073/pnas.91.26.12706. Proc Natl Acad Sci U S A. 1994. PMID: 7809106 Free PMC article.

7

Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.

Inglese J, Luttrell LM, Iñiguez-Lluhi JA, Touhara K, Koch WJ, Lefkowitz RJ. Inglese J, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3637-41. doi: 10.1073/pnas.91.9.3637. Proc Natl Acad Sci U S A. 1994. PMID: 8170960 Free PMC article.

8

A beta-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination.

Schleicher S, Boekhoff I, Arriza J, Lefkowitz RJ, Breer H. Schleicher S, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1420-4. doi: 10.1073/pnas.90.4.1420. Proc Natl Acad Sci U S A. 1993. PMID: 8381966 Free PMC article.

9

Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer.

Akhter SA, Skaer CA, Kypson AP, McDonald PH, Peppel KC, Glower DD, Lefkowitz RJ, Koch WJ. Akhter SA, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12100-5. doi: 10.1073/pnas.94.22.12100. Proc Natl Acad Sci U S A. 1997. PMID: 9342369 Free PMC article.

10

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.

Premont RT, Claing A, Vitale N, Freeman JL, Pitcher JA, Patton WA, Moss J, Vaughan M, Lefkowitz RJ. Premont RT, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14082-7. doi: 10.1073/pnas.95.24.14082. Proc Natl Acad Sci U S A. 1998. PMID: 9826657 Free PMC article.

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