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Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice.
Creemers EE, Davis JN, Parkhurst AM, Leenders P, Dowdy KB, Hapke E, Hauet AM, Escobar PG, Cleutjens JP, Smits JF, Daemen MJ, Zile MR, Spinale FG. Creemers EE, et al. Among authors: cleutjens jp. Am J Physiol Heart Circ Physiol. 2003 Jan;284(1):H364-71. doi: 10.1152/ajpheart.00511.2002. Epub 2002 Sep 26. Am J Physiol Heart Circ Physiol. 2003. PMID: 12388239 Free article.
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.
Heymans S, Luttun A, Nuyens D, Theilmeier G, Creemers E, Moons L, Dyspersin GD, Cleutjens JP, Shipley M, Angellilo A, Levi M, Nübe O, Baker A, Keshet E, Lupu F, Herbert JM, Smits JF, Shapiro SD, Baes M, Borgers M, Collen D, Daemen MJ, Carmeliet P. Heymans S, et al. Among authors: cleutjens jp. Nat Med. 1999 Oct;5(10):1135-42. doi: 10.1038/13459. Nat Med. 1999. PMID: 10502816
Reverse remodeling of the myocardial extracellular matrix after prolonged left ventricular assist device support follows a biphasic pattern.
Bruggink AH, van Oosterhout MF, de Jonge N, Ivangh B, van Kuik J, Voorbij RH, Cleutjens JP, Gmelig-Meyling FH, de Weger RA. Bruggink AH, et al. Among authors: cleutjens jp. J Heart Lung Transplant. 2006 Sep;25(9):1091-8. doi: 10.1016/j.healun.2006.05.011. Epub 2006 Aug 2. J Heart Lung Transplant. 2006. PMID: 16962471
137 results